Table 2. The association between clinicopathological characteristics and expression of RAB11B.
| Factors | No of tissues (n = 145), n (%) | RAB11B expression | Pb value | |
|---|---|---|---|---|
| Low (n = 71), n (%) | High (n = 74), n (%) | |||
| Age | ||||
| ≤ 20 | 50 (34.5) | 18 (36.0) | 32 (64.0) | 0.023 |
| > 20 | 95 (65.5) | 53 (55.8) | 42 (44.2) | |
| Gender | ||||
| Male | 91 (62.8) | 49 (53.8) | 42 (46.2) | 0.127 |
| Female | 54 (37.2) | 22 (40.7) | 32 (59.3) | |
| Location | ||||
| Tibia/femur | 98 (67.6) | 44 (44.9) | 54 (55.1) | 0.157 |
| Elsewhere | 47 (32.4) | 27 (57.4) | 20 (42.6) | |
| Histological type | ||||
| Osteoblastoma | 99 (68.3) | 43 (43.4) | 56 (56.6) | 0.051 |
| Else | 46 (31.7) | 28 (60.9) | 18 (39.1) | |
| Differentiated degree | ||||
| High/middle | 52 (35.9) | 36 (69.2) | 16 (30.8) | < 0.001 |
| Low/undifferentiation | 93 (64.1) | 35 (37.6) | 58 (62.4) | |
| TNM | ||||
| T1N0M0 | 26 (17.9) | 10 (38.5) | 16 (61.5) | 0.237 |
| T2N0M0 | 119 (82.1) | 61 (51.3) | 58 (48.7) | |
| Clinical stage | ||||
| I | 27 (18.6) | 19 (70.4) | 8 (29.6) | 0.014 |
| II | 118 (81.4) | 52 (44.1) | 66 (55.9) | |
bPearson Chi-Square P value.
The expression of RAB11B is reflected by the histochemistry score(H-score).H-score is equal to Σ(pi*i), which the ‘pi’ means the percentage of RAB11B-positive cells in the section and the ‘i’ means the tint strength of the cells. And the H-score cut-off based on the median of the H-score of 145 osteosarcoma tissues and classed as low(H-score ≤ 25) or high(H-score > 25) RAB11B expression.