Table 3A.
Select S. Typhi genes upregulated after 2 h infection.
| pGene | Gene | Log fold change | q-Value | Function |
|---|---|---|---|---|
| T_RS16275 | t3210 | 3.72 | 0.0004 | Preprotein translocase subunit SecG |
| T_RS09445 | t1853 | 3.43 | 0.0004 | Beta-hydroxydecanoyl-ACP dehydratase |
| T_RS18075 | t3559 | 3.38 | 0.0004 | Repressor of the Cpx envelope stress response pathway. |
| T_RS24905 | T_RS24905 | 3.38 | 0.0004 | Hypothetical protein |
| T_RS20765 | t4085 | 3.35 | 0.0004 | Preprotein translocase subunit SecY |
| T_RS24820 | T_RS24820 | 3.22 | 0.0004 | Hypothetical protein |
| T_RS24855 | T_RS24855 | 3.16 | 0.0004 | Hypothetical protein |
| T_RS04520 | t0882 | 3.13 | 0.0004 | Cold-shock protein CspJ |
| T_RS23945 | T_RS23945 | 3.1 | 0.0004 | Hypothetical protein |
| T_RS24535 | T_RS24535 | 3.02 | 0.0004 | Hypothetical protein |
| T_RS20790 | t4090 | 2.97 | 0.0004 | DNA-directed RNA polymerase subunit alpha |
| T_RS22875 | t4496 | 2.93 | 0.0021 | Pyrbi operon leader peptide |
| T_RS19685 | t3869 | 2.83 | 0.0004 | Hypothetical protein |
| T_RS23875 | T_RS23875 | 2.71 | 0.0004 | Hypothetical protein |
| T_RS01565 | t0310 | 2.71 | 0.0004 | Inositol monophosphatase |
| T_RS03930 | t0780 | 2.7 | 0.0004 | Glucose-1-phosphate cytidylyltransferase |
| T_RS19190 | t3772 | 2.67 | 0.0004 | Xanthine permease |
| T_RS03270 | t0646 | 2.6 | 0.0039 | Membrane protein |
| T_RS03285 | t0650 | 2.59 | 0.0004 | Phosphoenolpyruvate dependent, sugar transporting phosphotransferase system. |
| T_RS03290 | t0649 | 2.59 | 0.0004 | Phosphofructokinase |
| T_RS02365 | t0466 | 2.58 | 0.0004 | Acyltransferase |
| T_RS10080 | T_RS10080 | 2.57 | 0.0011 | Hypothetical protein |
| T_RS10085 | t1980 | 2.57 | 0.0011 | Translation initiation factor IF-1 |
| T_RS08805 | t1730 | 2.56 | 0.0004 | Hypothetical protein |
| T_RS22990 | t4521 | 2.53 | 0.0004 | Hypothetical protein |
| T_RS22995 | t4519 | 2.53 | 0.0004 | Serine/threonine protein kinase |
| T_RS23000 | t4520 | 2.53 | 0.0004 | Serine/threonine protein kinase |
| T_RS19345 | t3803 | 2.53 | 0.0004 | LPS core heptose(II) kinase RfaY |
| T_RS05655 | t1106 | 2.49 | 0.0004 | Hypothetical protein |
| T_RS02155 | T_RS02155 | 2.48 | 0.0004 | |
| T_RS08555 | t1680 | 2.46 | 0.0016 | Sodium‑potassium/proton antiporter ChaA |
| T_RS03960 | t0786 | 2.44 | 0.0004 | Glycosyl transferase |
| T_RS08780 | t1725 | 2.44 | 0.0004 | Beta-ketoacyl-ACP reductase |
| T_RS02535 | t0501 | 2.43 | 0.0004 | Colicin V production protein |
| T_RS20635 | t4059 | 2.42 | 0.0004 | Elongation factor G |
| T_RS03925 | t0779 | 2.39 | 0.0004 | CDP-6-deoxy-delta-3,4-glucoseen reductase |
| T_RS14115 | t2782 | 2.39 | 0.0004 | Hypothetical protein |
| T_RS16300 | t3215 | 2.38 | 0.0004 | RNA binding protein found associated to pre-50S subunit of the ribosome.* |
| T_RS22250 | t4371 | 2.38 | 0.0004 | Integrase |
| T_RS03965 | t0787 | 2.37 | 0.0004 | Glycosyl transferase |
| T_RS22890 | t4499 | 2.36 | 0.0004 | Ornithine carbamoyltransferase |
| T_RS12270 | t2413 | 2.36 | 0.0004 | Trigger factor |
| T_RS08595 | t1688 | 2.35 | 0.0004 | Adenylosuccinate lyase |
| T_RS21345 | t4196 | 2.34 | 0.0004 | Hypothetical protein |
| T_RS00790 | t0157 | 2.34 | 0.0004 | Pyruvate dehydrogenase complex repressor |
| T_RS17570 | t3461 | 2.31 | 0.0004 | DNA-binding protein HU-alpha |
| T_RS16745 | t3300 | 2.31 | 0.0004 | Fis family transcriptional regulator |
| T_RS12085 | t2377 | 2.31 | 0.0004 | Adenine phosphoribosyltransferase |
| T_RS00330 | t0067 | 2.3 | 0.0004 | Carbamoyl-phosphate synthase small subunit |
| T_RS00865 | t0172 | 2.29 | 0.0004 | Hypothetical protein |
| T_RS03955 | t0785 | 2.27 | 0.0004 | Transporter |
| T_RS16250 | t3205 | 2.27 | 0.0004 | Transcription termination protein NusA |
| T_RS03175 | t0627 | 2.26 | 0.0004 | Hypothetical protein |
| T_RS14120 | t2783 (iacP) | 2.23 | 0.0004 | Acyl carrier protein |
| T_RS12185 | t2397 | 2.22 | 0.0004 | Nitrogen regulatory protein P-II 2 |
| T_RS03945 | t0784 | 2.21 | 0.0004 | CDP-paratose 2-epimerase |
| T_RS03950 | t0783 | 2.21 | 0.0004 | CDP-paratose synthase |
| T_RS19320 | t3798 | 2.21 | 0.0004 | Hypothetical protein |
| T_RS19325 | t3799 | 2.21 | 0.0004 | Hypothetical protein |
| T_RS03940 | t0782 | 2.18 | 0.0004 | LPS biosynthesis protein |
| T_RS09545 | t1875 | 1.62 | 0.0067 | Hypothetical protein |
| T_RS00205 | t0042 | 1.61 | 0.0004 | Transcriptional activator NhaR |
| T_RS22130 | t4347 | 1.57 | 0.0004 | Vi polysaccharide export inner-membrane protein VexB |
| T_RS22140 | t4350 | 1.56 | 0.0037 | Vi polysaccharide biosynthesis protein TviD |
| T_RS22145 | t4349 | 1.56 | 0.0037 | Vi polysaccharide biosynthesis protein TviE |
For the full list of upregulated STY genes, please see Supplementary Table 2.
For the full list of upregulated STY genes, please see Supplementary Table 2.