Fig. 2.

Significant Molecules in Validation Cohort. (a) Violin plots showing overall abundance of significant urinary molecules in TB cases (TB) (n = 50) verses controls with pulmonary disease from other causes (C) (n = 50). Each color represents a distinct molecule shown in table. Darker black line represents 25th and 75th percentile. White line represents median value. Values are scaled to mean and log2 transformed. Values are shown in log2 scale. Wilcoxon rank sum test *p-value < 0.05, **p value < 0.001. (b) Receiver operator characteristic (ROC) curve of 10 significant molecules in validation cohort of 50 TB cases and 50 controls with pulmonary disease from other causes. Each color represents a distinct molecule shown in table. (c) Table of molecules. Masses listed as mass to charge ratio (m/z) in positive mode. Retention time (RT) is listed in minutes.