Skip to main content
. 2018 May 3;67(7):1297–1309. doi: 10.2337/db17-1509

Figure 8.

Figure 8

Reduced lipid accumulation in livers of ob/ob Pik3r1 R649W mice. Liver weight (A) and liver triglycerides (B) measured at 8 weeks of age in ob/ob and ob/ob-KI mice. Results are shown as mean ± SEM. **P < 0.01, ***P < 0.001, #P < 0.0005, one-way ANOVA. C: Liver sections stained with hematoxylin and eosin. Scale bars, 200 μm. mRNA expression of genes involved in de novo lipogenesis (D), fatty acid oxidation (E), β-oxidation (F), gluconeogenesis (G), and inflammation (H) in liver at 8 weeks of age. mRNA results are mean ± SEM of four to six animals per group. *P < 0.05, **P < 0.01, ***P < 0.001, #P < 0.0005 compared with controls, t tests.