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. 2018 Apr 3;23(4):818. doi: 10.3390/molecules23040818

Table 4.

ANOVA of the central composite design.

Source Sum of Squares df Mean Square F-Value p-Value Significance
Model 8.140 9 0.900 7.60 0.0020 Significant
X1 1.560 1 1.560 13.12 0.0047
X2 2.840 1 2.840 23.84 0.0006
X3 0.970 1 0.970 8.18 0.0170
X1X2 0.043 1 0.043 0.37 0.5591
X1X3 0.005 1 0.005 0.04 0.8409
X2X3 0.630 1 0.630 5.33 0.0437
X12 0.470 1 0.470 3.94 0.0752
X22 1.160 1 1.160 9.73 0.0109
X32 0.840 1 0.840 7.08 0.0239
Residual 1.190 10 0.120
Lack of Fit 0.200 5 0.040 0.20 0.9474 Not significant
Pure Error 0.990 5 0.200
Cor Total 9.330 19