Table 2.

Bactericidal activity of pooled antisera against rT-Nm-MIP (M2) protein delivered in different liposomes formulations. The titres are expressed as the reciprocal of the highest dilution at which 50% killing was observed. Human complement (HC, 25% [v/v]) or normal human serum (HS, 17% [v/v]) were used as exogenous complement sources for meningococcal and gonococcal strains, respectively. Data are the median values, with the range of values in parentheses, for HC-SBA from 3 to 4 independent measurements of bactericidal activity of all pooled serum samples. Single values denote that the HC-SBA titres from the independent experiments were identical. Significantly high bactericidal activities relative to the corresponding controls are highlighted in red. Sera from sham-immunized mice (controls) and normal mouse serum (NMS) showed no significant bactericidal activity. Strains MS11 and 12CFX_T_003 are serum sensitive. ND, not determined.