Table 4.
Statistical comparison of PrimAlign with the others
| Aligner | Weighted | KO | GO | EN | IP | CE-F | CE-O | LCCC-F | LCCC-O |
|---|---|---|---|---|---|---|---|---|---|
| AlignMCL | No | *** | *** | ** | ** | ||||
| AlignMCL | Yes | *** | *** | ** | ** | ||||
| AlignNemo | No | *** | *** | *** | *** | *** | *** | *** | *** |
| AlignNemo | Yes | *** | *** | *** | *** | *** | *** | *** | *** |
| CUFID | No | *** | *** | *** | *** | *** | *** | *** | *** |
| CUFID | Yes | *** | *** | *** | *** | *** | *** | *** | *** |
| HubAlign | No | *** | *** | *** | *** | *** | *** | *** | *** |
| IsoRankN | No | *** | *** | *** | *** | *** | *** | ||
| MAGNA++ | No | *** | *** | *** | *** | *** | *** | *** | *** |
| MI-GRAAL | No | NA | NA | NA | NA | NA | NA | NA | NA |
| NETAL | No | *** | *** | *** | *** | *** | *** | *** | *** |
| NetCoffee | No | *** | *** | *** | *** | *** | *** | *** | *** |
| NetworkBLAST | No | *** | *** | *** | *** | *** | *** | *** | *** |
| NetworkBLAST | Yes | *** | *** | *** | *** | *** | *** | *** | *** |
| PINALOG | No | *** | *** | *** | *** | *** | *** | *** | *** |
| SANA | No | *** | *** | *** | *** | *** | *** | *** | *** |
| SMETANA | No | *** | *** | *** | *** | *** | *** | *** | *** |
| SMETANA | Yes | *** | *** | *** | *** | *** | *** | *** | *** |
| WAVE | No | *** | *** | *** | *** | *** | *** | *** | *** |
Notes: Statistical comparison of differences in evaluation measures between PrimAlign with unweighted networks on input and the other algorithms for human-yeast alignment. (empty field) P > 0.05
*
P ≤ 0.05
**
P ≤ 0.01
***
P ≤ 0.001. Green = improvement.