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. 2018 Jun 19;8(2):42. doi: 10.3390/biom8020042

Table 1.

The best characterized calcium-binding proteins involved in biomineralization.

Protein Symbol Protein Name Organism Function Swiss Prot ID
OPN (SSP1) Osteopontin, secreted phosphoprotein 1 Homo sapiens Matrix mineralization, immunity P10451
DMP1 Dentin matrix protein 1 Homo sapiens Osteoblast differentiation, nucleation of hydroxyapatite Q13316
MEPE Matrix extracellular phosphoglycoprotein Homo sapiens Phosphate excretion, mineralization Q9NQ76
BSP Bone sialoprotein Homo sapiens Matrix mineralization, hydroxyapatite binding, cell attachment P21815
DSPP Dentin sialophosphoprotein Homo sapiens Dentinogenesis Q9NZW4
AMELX Amylogenin Homo sapiens Enamel formation; extracellular scaffold, crystal growth Q99217
Stm Starmaker Danio rerio (zebrafish) Otolith formation A2VD23
OMM-64 Otolith matrix macromolecule-64 Oncorhynchus mykiss (rainbow trout) Otolith formation B1Q2L9