Table 1.
Patient Characteristics
| Characteristic | (N = 70) |
|---|---|
| Mean age (SD), y | 60.5 (11.3) |
| Male, No. (%) | 39 (55.7) |
| Ever smoker, No. (%) | 24 (34.3) |
| Surgical lung biopsy, No. (%) | 55 (78.6) |
| Exposure, No. (%) | |
| Mold | 20 (28.6) |
| Bird | 11 (15.7) |
| Down feather products | 6 (8.6) |
| Othera | 4 (5.7) |
| Unknown | 29 (41.4) |
| Pulmonary function at MMF or AZA initiation | |
| Mean FVC % predicted (SD) | 65.2 (18.0) |
| Mean Dlco % predicted (SD) | 49.8 (15.2) |
| MMF, No. (%) | 51 (72.9) |
| Daily dose, range, mg | 1,000-3,000 |
| AZA, No. (%) | 19 (27.1) |
| Daily dose, range, mg | 100-150 |
| Mean dose (SD), mg | 114.9 (23.1) |
| Prednisone, No. (%) | 59 (84.3) |
| Dose, range, mg | 10-30 |
| Patients treated with prednisone prior to MMF or AZA initiation, No. (%) | 14 (23.0) |
| Prednisone dose at MMF or AZA initiation, mg | 12.33 (13.99) |
| Prednisone dose at 6 mo after MMF or AZA initiation, mg | 3.75 (5.25) |
AZA = azathioprine; Dlco = diffusing capacity for carbon monoxide; MMF = mycophenolate mofetil.
a
Other exposures included swamp cooler (n = 1), farming products (n = 1), and hot tub (n = 2).