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. 2018 Mar 29;6(2):21. doi: 10.3390/toxics6020021

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© 2018 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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GSEA enrichment plots for transcriptional changes in gonadal adipose tissue of mice exposed perinatally to BDE-47: (A) bile acid metabolism gene set; (B) genes targets of HNF4A; and (C) genes targets of SREBF. GSEA plot legend: 1—running enrichment score for the gene set; 2—vertical lines show where the members of the gene set appear in the ranked list of genes; 3 and 4—ranked list of differentially expressed genes from the most up-regulated (left of each plot) to the most downregulated (right of each plot). Regulation is shown in the heat-bar (3) and in the bar plot (4).