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. 2018 Mar 30;10(2):41. doi: 10.3390/pharmaceutics10020041

Figure 2.

Figure 2

Figure 2

Chromatograms of (A) blank rat plasma; (B) plasma spiked with IS (200 ng/mL); (C) plasma spiked with procainamide (20 ng/mL, lower limit of quantification (LLOQ)) and IS (200 ng/mL); (D) plasma spiked with N-acetylprocainamide (20 ng/mL, LLOQ) and IS (200 ng/mL); (E) plasma spiked with procainamide (1000 ng/mL) and IS (200 ng/mL); (F) plasma spiked with N-acetylprocainamide (500 ng/mL) and IS (200 ng/mL) and (G) 30 min after intravenous administration of procainamide hydrochloride (10 mg/kg). PA: procainamide, NAPA: N-acetylprocaiamide, IS: internal standard.