Fig. 1.

OncoPPi Portal overview. The OncoPPi Portal provides a web-based interface to explore, visualize and export the network of experimentally determined cancer-associated PPIs. To facilitate prioritization of PPIs for further biological studies, the PPI network is integrated with genomics, pharmacological and structural data. A direct connection of PPIs and individual proteins with external resources enable detailed protein annotations and efficient data mining. Together, the OncoPPi Portal provides a framework to generate new hypotheses and biological models for cancer target discovery