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. 2018 Mar 7;72(7):605–610. doi: 10.1136/jech-2017-209681

Intimate partner violence against low-income women in Mexico City and associations with work-related disruptions: a latent class analysis using cross-sectional data

Jhumka Gupta 1, Tiara C Willie 2,3, Courtney Harris 1, Paola Abril Campos 4, Kathryn L Falb 5, Claudia Garcia Moreno 6, Claudia Diaz Olavarrieta 7, Cassandra A Okechukwu 4
PMCID: PMC6031258  PMID: 29514921

Abstract

Background

Disrupting women’s employment is a strategy that abusive partners could use to prevent women from maintaining economic independence and stability. Yet, few studies have investigated disruptions in employment among victims of intimate partner violence (IPV) in low-income and middle-income countries. Moreover, even fewer have sought to identify which female victims of IPV are most vulnerable to such disruptions.

Methods

Using baseline data from 947 women in Mexico City enrolled in a randomised controlled trial, multilevel latent class analysis (LCA) was used to classify women based on their reported IPV experiences. Furthermore, multilevel logistic regression analyses were performed on a subsample of women reporting current work (n=572) to investigate associations between LCA membership and IPV-related employment disruptions.

Results

Overall, 40.6% of women who were working at the time of the survey reported some form of work-related disruption due to IPV. LCA identified four distinct classes of IPV experiences: Low Physical and Sexual Violence (39.1%); High Sexual and Low Physical Violence class (9.6%); High Physical and Low Sexual Violence and Injuries (36.5%); High Physical and Sexual Violence and Injuries (14.8%). Compared with women in the Low Physical and Sexual Violence class, women in the High Physical and Sexual Violence and Injuries class and women in the High Physical and Low Sexual Violence and Injuries class were at greater risk of work disruption (adjusted relative risk (ARR) 2.44, 95% CI 1.80 to 3.29; ARR 2.05, 95% CI 1.56 to 2.70, respectively). No other statistically significant associations emerged.

Conclusion

IPV, and specific patterns of IPV experiences, must be considered both in work settings and, more broadly, by economic development programmes.

Trial registration number

NCT01661504.

Keywords: violence against women, Mexico, employment, latent class analysis, economic empowerment, Latin America

Background

Male-perpetrated intimate partner violence (IPV) against women is a pervasive global health issue with nearly one in three women experiencing such violence in their lifetime.1 In addition to impacting health outcomes (eg, reproductive and mental health), IPV adversely effects other important global development domains.1 Though research is skewed towards samples from the USA and other high-income countries, studies increasingly demonstrate that IPV has negative economic consequences for women’s employment outcomes (eg, difficulties with finding and sustaining employment, work productivity) among women with IPV experiences.2–5 This may be due to abusive partners’ interference with women’s employment through harassment and other job interference tactics.5 Moreover, one national US-based study of women’s workplace homicides identified IPV as the second major cause of such deaths.6

To date, research on IPV’s impacts on women’s employment and other income-generating activities within low-income and middle-income countries (LMICs) is scarce. Much existing research pertaining to women’s employment and IPV in LMICs is framed around women’s employment status as being a risk factor for IPV, and IPV as a barrier to help-seeking and/or escaping an abusive partner.7–10 Less is known about how IPV may impact women’s employment. One Nigeria-based study with women employed in the communications, trade, teaching and civil service industries found that IPV was significantly related to decreased work productivity.11 The extent to which these associations extend to lower-income women in other LMICs is currently unclear.

Understanding the impact of IPV on women’s employment outcomes in Mexico is warranted. Although Mexico made progress towards its indicators for the Millennium Development Goals pertaining to gender and women’s empowerment, a national survey documented IPV to be at 33%.12 Moreover, national data found 37.8% of economically active Mexican women reported some form of past-year IPV,12 and higher experiences of severe violence have been documented among women who are employed outside the home.13–15 The investigation of the impact of IPV on employment among lower- income women in Mexico is particularly critical, given limited financial resources and greater dependency on abusive partners.12 Furthermore, 51% of the informal self-employed workers are women.16

Furthermore, even less is known about which groups of women may be at greatest risk for employment disruptions. For instance, women who experience higher severity of IPV are more likely to face revictimisation, injuries and poorer health.17–19 These potential effects may make employment maintenance difficult. Growing US-based research has used person-centred approaches such as latent class analysis (LCA), to identify subgroups of women based on their patterns of IPV experiences, and relations to select health outcomes and resource use.20–23 Research using LCA with samples from LMICs is also emerging.24 Identifying groups of women via LCA may help inform development of targeted interventions. Achieving gender equality by providing equal access to decent work are key targets for the 2030 Sustainable Development Goals,25 but some subgroups of women based on IPV experiences may be at a greater disadvantage to realise targets.

The current study uses baseline data from a nurse-delivered randomised controlled trial with IPV survivors presenting to community health centres in Mexico City26 to conduct the following aims: (1) use LCA to identify distinct groups of women based on past-year physical and sexual IPV experiences, and (2) assess associations between LCAs with disruptions in paid work due to IPV.

Methods

The study used baseline data from a completed randomised controlled trial (RCT) with 42 community health clinics serving low-income women in Mexico City. Details on the trial and study protocols are detailed elsewhere (see online supplementary file of RCT findings and protocol paper)26 27 and are briefly summarised. The RCT aimed to assess the impact of a nurse-delivered intervention to women identified as experiencing recent IPV through screening within public health clinics in Mexico City. All study protocols were approved by Yale School of Public Health (no. 1202007993), George Mason University (protocol no. 704016-4), Innovations for Poverty Action (no. 00006083) and the Mexico City Ministry of Health (protocol no. 1470-6812) human subjects committees.

Study setting

The study took place in Mexico City, the capital and most populous urban centre where almost half of the population is uninsured (approximately 3 859 963 residents).28 The uninsured population receives healthcare through a federal healthcare programme at Ministry of Health (MoH) clinics in Mexico City. The Mexico City MoH health system comprises 206 health clinics (types I, II and III) and 31 hospitals. Type III clinics, the clinics selected for the RCT, offer more services and have a greater patient volume.

Participants

Eligible women were ages 18–44 years, in a current heterosexual relationship, responded in affirmative to past-year sexual or physical IPV, and were not pregnant or pregnant in their first trimester. Study exclusion criteria included cognitive impairment, seeking treatment for life-threatening emergency care or intending to relocate within 2 years. Trained female research assistants approached women in clinic waiting rooms, verified study eligibility and asked women to take an assessment screening that contained items from an abuse assessment screen that is widely used by International Planned Parenthood Federation/Western Hemisphere Region in Latin American and Caribbean countries including Mexico.29 30 Based on piloting feedback, the final tool consisted of 11 questions in order to build rapport between the research assistant and participant (see online supplementary material for full assessment tool).27 If a woman answered at least one affirmative response to the validated physical and/or sexual IPV items, they were invited to participate in the study; those interested completed written and/or verbal informed consent. Both the assessment and informed consent process took place within a private area of the clinic. A total of 29 947 women presenting at the participating 42 clinics were approached and screened for eligibility. The baseline participation rate was 83.6% among women who could be determined to be eligible, for a total of 950 participants.26 Three additional women were excluded from the current analytic sample due to incomplete responses to all IPV items, yielding 947 women.

Supplementary file 2

jech-2017-209681supp002.pdf (1.1MB, pdf)

Measures

Paid work disruption

To assess frequency of past-year work disruptions due to past-year IPV, participants were asked: “As a result of the abuse have you lost your job?”; “As a result of the abuse have you missed work?”; and “As a result of the abuse did you have to change jobs or schools?” A binary variable was then created (yes to any versus no to all).

Latent class indicators of IPV experiences

Past-year physical and/or sexual IPV and injuries were reported by women. IPV and injuries were assessed using items from the WHO Multi-Country study on Women’s Health and Domestic Violence.31 Women were asked whether they experience various acts of physical and sexual violence by the male partners and if injuries occurred as a result of the violence. Past-year physical IPV was assessed by whether a woman reported whether her male partner had done the following: slapped her or thrown something at her that could hurt her; pushed, shoved, kicked or dragged her; choked her, strangled her or burned her intentionally; threatened to use a gun, knife or other weapon against her; and used a gun, knife or other weapon against her in the past year. Past-year sexual IPV was assessed by whether a woman reported her male partner had forced to have sex because of threats or intimidation or physically forced to have sex by their intimate partner when she did not want to. Injuries were assessed by whether a woman reported experiencing the following due to past year IPV: cuts that required stitches, a broken bone, lost tooth, burns, bruises, passed out or lost consciousness, and aches and pains. An affirmative response was coded as experiencing that specific past-year physical and/or sexual IPV behaviour and injury, while ‘no’ to all items was coded as no IPV. A binary variable was created for each specific form of IPV and injury.

Demographics and work status

Women were asked to report demographics such as age, number of children, birthplace, occupation, prior screening for IPV in the health sector, relationship status and reason for healthcare visit. A ‘work status’ variable was derived from three questions. First, we assessed women’s involvement in the formal sector by asking women what their main occupation was with response options as ‘Employee, Student, Housewife, Looking for Work, Own Personal Business’. Second, we assessed women’s involvement in the informal sector by asking women, in addition to their main occupation, whether they do the following activities: ‘Helping Family Business, Selling or Making Products, Animal Husbandry, Student, Employed in Other Sectors, or Other Activities (like ironing, car care, washing)’. Third, women were asked if they received any money or income for the activities they mentioned before. Women who said ‘Yes’ to receiving money or income for their activities in the formal and informal sectors were included in the analysis.

Data analysis

We performed descriptive statistics of types of IPV, demographics and the outcomes. All analyses were conducted using SAS V.9.4 (SAS Institute, Cary, North Carolina, USA).

Next, we conducted a series of latent class models using the 14 IPV indicators. Each model’s fit was assessed using the likelihood ratio test G2, the Akaike information criterion (AIC) and the adjusted Bayesian information criterion (ABIC). Smallest values for AIC and ABIC, and a non-significant P value for G2 suggest better model fit.21 We also evaluated the entropy and model identification was assessed by running the models with 1000 randomly selected starting values and reviewing the percentage of times the model converged at the highest log-likelihood value. An entropy equal to or greater than 0.80 suggest adequate classification properties of the model.32 PROC LCA and LTA add-on software to SAS V.9.4 (SAS Institute) was used to fit the latent class models while accounting for clustering.33 The names of the latent classes were based on the probability of the indicators relative to 0.50 (ie, high >0.50, low <0.50).21

Separate multilevel risk regression analyses were used to examine unadjusted and adjusted models testing the effects of latent class membership on paid work disruption. We used multilevel modelling to address clustering in the data (ie, individuals were nested within health clinics). The generalised mixed model in GENMOD procedure was used to fit the multilevel models with a Poisson distribution for optimising precision.34 Each risk regression model adjusted for age, number of children, birthplace, occupation, IPV screening, educational status, relationship status and reason for healthcare visit. Relative risk (RR), 95% CIs and P values <0.05 were used to assess significance. These analyses were restricted to women who reported working, resulting in a subsample of 572.

Results

Participant characteristics

On average, participants who worked in the past year were 30 years old (SD 7.23 years) and had two children (SD 1.23 children) (table 1). A total of 72.4% were born in Mexico City, and most were in a common law marriage (63.1%) or married (26.4%). Further details are in table 1.

Table 1.

Participant characteristics of IPV survivors in Mexico City presenting to study clinics (total sample and subset that reported paid work in the year preceding the survey)

Total sample that derived latent classes
N (%)
Subset of total sample that worked in the past year n (%)
Overall 947 (100.0) 572 (60.4)
Age, M (SD) 29.86 (7.16) 30.71 (7.23)
No of children, M (SD) 2.20 (1.20) 2.21 (1.23)
Birthplace
 Mexico City 677 (71.5) 414 (72.4)
 State of Mexico, other republic or abroad 270 (28.5) 158 (27.6)
 Previously screened for IPV in healthcare setting 95 (10.0) 64 (11.2)
Relationship status
 Single 57 (6.0) 43 (4.5)
 Married 227 (23.9) 151 (26.4)
 Common-law marriage 635 (67.1) 361 (63.1)
 Separated and/or divorced 28 (2.9) 17 (2.9)
Reason for healthcare visit*†
 General consultation 232 (24.6) 150 (26.3)
 Gynaecology 70 (7.4) 44 (7.7)
 Other services 643 (68.0) 377 (66.0)
Work status
 Own personal or help family business 59 (6.2) 59 (10.3)
 Selling/making products 166 (17.5) 166 (29.0)
 Animal husbandry or fieldwork 2 (0.2) 2 (0.3)
 Students 11 (1.2) 11 (1.9)
 Multiple informal jobs 163 (17.2) 163 (28.5)
 Employed, non-specified category 171 (18.1) 171 (29.9)
 Housewife (no paid work) 357 (37.7) NA
 Looking for work (no paid work) 18 (1.9) NA
Education
 No schooling 26 (2.8) 18 (3.2)
 Primary and secondary 604 (63.8) 359 (62.8)
 High school and beyond 317 (33.5) 195 (34.1)
Physical IPV
 Pushed and shoved 869 (91.8) 529 (92.9)
 Twisted and kicked 423 (44.7) 258 (45.1)
 Hit or thrown object 251 (26.5) 165 (28.9)
 Burned and threats of weapon use 86 (9.1) 55 (9.6)
 Hit with fist 434 (45.8) 265 (46.3)
 Choked or strangled 283 (29.9) 175 (30.6)
Sexual IPV
 Forced sex by threats 207 (21.9) 125 (21.9)
 Sex by intimidation 279 (29.5) 176 (30.8)
 Sex by physical force 148 (15.6) 103 (18.0)
Injuries
 Broken bones and teeth 56 (5.9) 37 (6.5)
 Burns and stitches 50 (5.3) 35 (6.1)
 Bruises 592 (62.5) 364 (63.6)
 Passed out 72 (7.6) 47 (8.2)
 Aches and pains 494 (52.2) 307 (53.7)
 Work-related disruptions NA 232 (40.6)

*Values are given as number (column percentage). Column percentages are rounded to nearest tenth and may not equal 100.

†Two cases missing on data for reason for visit and therefore not included in the table.

IPV, intimate partner violence; M, mean; NA, not applicable.

Identifying latent classes based on IPV experiences

IPV experiences for the entire sample are summarised in table 1. The LCA suggest four distinct classes based on experiences of IPV (figure 1). The four-class model was chosen because the P value for G2 was non-significant, and the AIC and ABIC test statistics were smallest. The entropy for the four-class model suggests that women were appropriately classified in their groups approximately 80% of the time. The four-class model was well defined, with 100.0% random sets producing the maximum-likelihood solution. Classes were named based on the proportion of violence experienced among women in their respective class. The Low Physical and Sexual IPV and Low Injuries class was the largest class accounting for 39.1% of the sample and comprised women reporting a low prevalence of physical and sexual IPV and injuries. The High Physical and Low Sexual IPV and Injuries class was the second largest class accounting for 36.5% of the sample and comprised women reporting a high prevalence of physical IPV and injuries and a low prevalence of sexual IPV. The High Physical and Sexual IPV and Injuries class was the third class accounting for 14.8% of the sample and comprised women reporting a high prevalence of physical and sexual IPV and injuries. The High Sexual and Low Physical IPV and Low Injuries class was the smallest class accounting for 9.6% of the sample and comprised women reporting a high prevalence of sexual IPV and a low prevalence of physical IPV and injuries.

Figure 1.

Figure 1

Forms and frequencies of physical and sexual intimate partner violence by latent class. IPV, intimate partner violence. The colour version of this figure is available online.

Associations between latent class membership and paid work disruptions due to IPV

Latent class membership was associated with work-related disruptions (table 2). The unadjusted analysis suggests that the risk of work-related disruptions was significantly higher among women in the High Physical and Sexual IPV and Injuries (RR 2.64, 95% CI 2.00 to 3.50) and women in the High Sexual and Low Physical IPV and Low Injuries (RR 2.08, 95% CI 1.58 to 2.72) compared with women in the Low Physical and Sexual IPV and Low Injuries class. Latent class membership in the High Physical and Sexual IPV and Injuries (adjusted relative risk (ARR) 2.44, 95% CI 1.80 to 3.29, P<0.001) and women in the High Sexual and Low Physical IPV and Low Injuries (ARR 2.05, 95% CI 1.56 to 2.70, P<0.001) remained significantly associated with violence disrupting work after adjustment.

Table 2.

Unadjusted and adjusted relative risk regression analyses of latent classes of IPV and work-related disruptions (n=572)

RR (95% CI) ARR (95% CI)
Latent classes
  High Physical/Sexual IPV and Injuries 2.64 (2.00 to 3.50)*** 2.44 (1.80 to 3.29)***
  High Physical/Low Sexual IPV and Injuries 2.08 (1.58 to 2.72)*** 2.05 (1.56 to 2.70)***
  Low Physical and Sexual IPV 1.00 1.00
  High Sexual and Low Physical IPV 1.03 (0.61 to 1.75) 0.92 (0.55 to 1.56)
Age 0.98 (0.97 to 0.99)** 1.02 (1.01 to 1.03)**
No of children 0.98 (0.92 to 1.03) 0.93 (0.86 to 1.02)
Birthplace
  Mexico City 1.04 (0.89 to 1.23) 0.94 (0.76 to 1.16)
  State of Mexico, other republic or abroad 1.00 1.00
Previously screened for IPV in healthcare setting 1.40 (1.05 to 1.87)* 1.11 (0.87 to 1.42)
Relationship status
  Single 0.99 (0.77 to 1.28) 0.99 (0.70 to 1.40)
  Married 0.96 (0.82 to 1.13) 0.95 (0.78 to 1.20)
  Common-law marriage 1.00 1.00
  Separated and divorced 2.06 (0.98 to 4.33) 1.38 (0.97 to 1.97)
Reason for healthcare visit
  General consultation 0.88 (0.75 to 1.04) 1.10 (0.90 to 1.35)
  Gynaecology 1.04 (0.82 to 1.32) 1.03 (0.67 to 1.57)
  Other services 1.00 1.00
Occupation
  Selling/making products 0.74 (0.56 to 0.96)* 0.78 (0.61 to 1.01)
  Multiple informal jobs 1.02 (0.81 to 1.29) 0.99 (0.79 to 1.23)
  Employed (type not specified) 1.00 1.00
  Other (personal/family business, fieldwork, students) 0.70 (0.48 to 1.02) 0.82 (0.57 to 1.18)
Education
  No schooling 1.00 1.00
  Primary and secondary 0.54 (0.23 to 1.28) 2.19 (0.88 to 1.57)
  High school and beyond 0.64 (0.27 to 1.55) 1.90 (0.77 to 1.59)

*P<0.05; **P<0.01; *** P<0.001.

ARR, adjusted RR; IPV, intimate partner violence; RR, relative risk.

Discussion

This clinic-based study found a high level of work-related disruption due to IPV among low-income women in Mexico City with recent IPV experiences. One in four women reported either having to change jobs, miss work or school, or losing their job due to the abuse they were experiencing. The findings underscore how IPV can impede engagement in paid work among IPV survivors and thus provides support for conceptualising IPV as a global economic and workplace health issue, in addition to a critical public health and human rights issue.

Four distinct classes of IPV experiences were identified. Few studies have examined patterns of IPV experiences within Mexico or other LMICs, thus direct comparisons are difficult. Nonetheless, findings are consistent with other work that underscores how the emergence of distinct classes and the use of using LCA to improve understanding of heterogeneity of IPV experiences among vulnerable women.24 35 For instance, while all women in the study sample had reported either physical or sexual violence during the year preceding the survey, neither levels of specific forms of IPV nor levels of injuries nor specific forms of violence were consistently experienced. Furthermore, high levels of injuries were only present in two classes (High Physical/Sexual IPV and Injuries; High Physical/Low Sexual IPV and Injuries), where there such injuries also occurred in combination with high levels of physical IPV. When high levels of sexual IPV were experienced, as in the High Sexual and Low Physical IPV class, low levels of both physical IPV and injury were also present; this class was also the smallest of the four classes. Notably, the largest class was the Low Physical IPV/Low Sexual IPV/Low Injuries class, followed by the High Physical IPV/Low Sexual IPV/Injuries class.

Importantly, latent classes of IPV experiences were differentially associated with work disruption. Women in the High Physical IPV/High Sexual IPV and Injuries had the greatest likelihood for reporting work-related disruptions in comparison to the Low Physical/Sexual IPV/Low Injuries class. Similarly, women in the High Physical/Low Sexual/Injuries class also had a greater likelihood for disruption, while the High Sexual/Low Physical/No Injuries class did not significantly differ in likelihood of work-related disruptions in comparison to the low IPV class. These findings suggest that work-related disruptions may be largely driven by the occurrence of injuries, in combination with high levels of other forms of IPV (physical and sexual). The presence of such injuries may disrupt work due to pain from violence severity and/or shame if the injuries are visible, as shame from injuries has been underscored in other studies.18 36 37 Furthermore, the presence of such injuries that occur in combination with high levels of physical and sexual IPV may also be a marker for severe IPV that poses the most direct threat to a woman’s safety and autonomy in other spheres, such as reproductive health,38 and thus may extend to higher levels of disruptions in paid work. Additional research is needed to explore such potential mechanisms, including injuries as a mediator, and to better understand why class 4 (High Sexual IPV/Low Physical IPV/No Injuries) did not significantly relate to increased work-related disruptions. It may be that the negative health impacts of belonging to this class may manifest with other health outcomes, such as mental health or reproductive health.

The current study has limitations. First, while the job-related disruptions specifically asked about whether disruptions occurred because of IPV, participants may have responded in the affirmative based on non-IPV-related factors. Also, the work-related disruption outcome was inclusive of one item that also included school-related disruptions. However, only two women identified as students and responded in the affirmative to the item that included school-related issues. The LCA classes are statistical constructs, thus additional research, including qualitative research, is needed. The analysis used a clinic-based sample composed of low-income women in Mexico City, with recent IPV experiences, who met specific criteria for inclusion into an RCT. Thus, the latent classes may be only generalisable to similar demographics reported herein. It is also possible that women may have experienced work-related disruptions due to IPV that occurred prior to the past 12 months. Lastly, despite attention to ethical and privacy concerns, IPV experiences may be under-reported, and this may influence the classes.

These limitations notwithstanding, the current study has several implications for programming and future research. Given the high levels of paid work disruption due to IPV in this clinic-based study, the health sector may seek to integrate work-related disruptions into ongoing responses to IPV. The high frequency of women who reported earning money through informal sectors also highlights the importance of outreach to women engaged in informal sector employment regarding IPV safety planning, outreach regarding resources and prevention interventions. Study findings herein strongly underscore the importance of understanding typologies of IPV experiences as a step towards informing more tailored programming. Future research is also needed to clarify underlying mechanisms through which the different patterns of IPV experiences impact work-related disruptions to better inform potential interventions, with a particular focus on injuries.

Furthermore, findings are consistent with existing research on the importance of addressing gender norms and IPV in economic empowerment programming, and thus underscores the importance of economic empowerment as a strategy for IPV prevention as well as reducing IPV to ensure economic development.39 40

What is already known on this subject.

  • Women’s employment status has been widely document as a risk factor for experiencing intimate partner violence. In high-income countries, research has also documented how intimate partner violence impacts women’s work outcomes (eg, job instability, absenteeism, lower productivity). Very little is known, however, how intimate partner violence and which specific patterns of intimate partner violence experiences impact women’s work outcomes in low-income and middle-income countries, such as Mexico.

What this study adds.

  • In Mexico City, a high frequency of work-related disruption due to intimate partner violence was documented among a clinic-based sample of low-income women who were survivors of intimate partner violence. Through latent class analysis, distinct patterns of violence experiences were identified. These patterns of intimate partner violence were also related to work disruption. This was one of the first studies to investigate basic patterning of intimate partner violence experiences and how such patterns relate to women’s work outcomes in a low-income and middle-income country. Study findings highlight the importance of considering women’s safety within work settings and, more broadly, economic development programming.

Supplementary file 1

jech-2017-209681supp001.pdf (1MB, pdf)

Acknowledgments

The authors thank the Mexico City Ministry of Health and MEXFAM for their collaboration. The authors would also like to thank Helena Acosta from International Planned Parenthood International for training the nurses in our study. The authors would also like to thank the women and nurses who participated in this study.

Footnotes

Contributors: JG had full access to all of the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis. Study concept and design: JG, TCW, CDO, CGM. Acquisition of data: JG, KLF, PAC, CDO. Analysis and interpretation of data: JG, TCW, KLF, PAC, CH, CDO, CGM, CAO. Drafting of the manuscript: JG, TCW. Critical revision of the manuscript for important intellectual content: JG, TCW, KLF, PAC, CH, CDO, CGM, CAO. Statistical analysis: TCW, JG. Obtained funding: JG, CDO. Administrative, technical or material support: JG, KLF, PAC, CDO.

Funding: The study was funded by an anonymous donor administered by the Vanguard Charitable Endowment Program. Based on the stipulations set forth by the donor, we are not permitted to disclose the funder (PI: JG). Partial support was also provided by NIMH to Yale Center for Interdisciplinary Research on AIDS (T32MH020031).

Disclaimer: The views expressed herein are solely those of the authors and do not necessarily represent the views, policies, or decisions of the NIH, NIMH, the MOH, or the World Health Organization.

Competing interests: None declared.

Patient consent: Obtained.

Ethics approval: All study protocols were approved by Yale School of Public Health (no. 1202007993), George Mason University (protocol no. 704016-4), Innovations for Poverty Action (no. 00006083) and the Mexico City Ministry of Health (protocol no. 1470-6812) human subjects committees.

Provenance and peer review: Not commissioned; externally peer reviewed.

Data sharing statement: Due to the sensitive nature of the data, the data cannot be made publicly available. Requests for data should be sent to JG.

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