Table 2.
Treatment | Age (yrs) | Body wt (kg) | Glucose (mg/dl) | Insulin (μIU/ml) | Ratio Glucose/Insulin |
---|---|---|---|---|---|
Untreated | 5.4 ± 0.3 | 13.4 ± 0.8 | 68 ± 2 | 6.6 ± 1.0 | 13.8 ± 3.4 |
Letrozole | 5.7 ± 0.3 | 14.3 ± 1.2 | 67 ± 2 | 12.0 ± 2.2* | 6.8 ± 1.3** |
Values are expressed as means ± SE on the day of iv glucose tolerance test in offspring from baboons untreated (n = 11) or treated on days 100–165/175 of gestation (term = 184 days) with letrozole (115 μg/kg body weight/day via maternal sc injection, n = 9)
P < 0.03 vs. untreated (Student “t” test)
P < 0.03 vs. untreated (Mann-Whitney “t” test)