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Morbidity and Mortality Weekly Report logoLink to Morbidity and Mortality Weekly Report
. 2018 Jul 13;67(27):753–757. doi: 10.15585/mmwr.mm6727a1

Subjective Cognitive Decline Among Adults Aged ≥45 Years — United States, 2015–2016

Christopher A Taylor 1,, Erin D Bouldin 1,2, Lisa C McGuire 1
PMCID: PMC6047468  PMID: 30001562

Subjective cognitive decline (SCD) is the self-reported experience of worsening or more frequent confusion or memory loss within the previous 12 months (1,2) and one of the earliest noticeable symptoms of Alzheimer’s disease (Alzheimer’s), a fatal form of dementia (i.e., a decline in mental abilities severe enough to interfere with everyday life) (1). Alzheimer’s is the most common form of dementia, although not all memory loss results from Alzheimer’s (3). To examine SCD, CDC analyzed combined data from the 2015 and 2016 Behavioral Risk Factor Surveillance System (BRFSS) surveys. Overall, 11.2% of adults aged ≥45 years reported having SCD, 50.6% of whom reported SCD-related functional limitations. Among persons living alone aged ≥45 years, 13.8% reported SCD; among persons with any chronic disease, 15.2% reported SCD. Adults should discuss confusion or memory loss with a health care professional who can assess cognitive decline and address possible treatments and issues related to chronic disease management, medical care, and caregiving.

BRFSS is a state-based, random-digit–dialed telephone survey of noninstitutionalized adults aged ≥18 years in all 50 states, the District of Columbia (DC), and several U.S. territories.* The six-question cognitive decline module (optional for states in 2015 and 2016) examines how SCD affects the life of respondents aged ≥45 years, including difficulties performing activities or caring for themselves. Overall, 49 states (all except Pennsylvania), Puerto Rico, and DC administered the module in one or both years. For five states that administered the module in both years, only 2016 data were included in this analysis. For the BRFSS surveys in 2015 and 2016, the overall combined landline and cellular telephone response rates among states, Puerto Rico, and DC ranged from 30.7% to 65.0% (median = 47.1%).

Respondents who answered affirmatively to the question “During the past 12 months, have you experienced confusion or memory loss that is happening more often or is getting worse?” were classified as having SCD. Respondents with SCD were asked if SCD caused them to give up day-to-day activities such as cooking, cleaning, taking medications, driving, or paying bills; how often they needed and could receive necessary assistance with those activities; how often SCD interfered with their ability to work, volunteer, or engage in social activities; and whether they had discussed SCD with a health care professional. Respondents who reported “always,” “usually,” or “sometimes” (as opposed to “rarely” or “never”) giving up day-to-day activities or interference with ability to work, volunteer, or engage in social activities were classified as having SCD-related functional limitations.

Data were examined by age group, sex, race/ethnicity, education level, veteran status, employment, and living alone. Chronic disease status was ascertained by history of heart disease; stroke, or cerebrovascular disease; asthma; lung disease; cancer (other than skin); arthritis; or diabetes. Data were analyzed using statistical software and methods that accounted for the complex survey design and weighted data. Prevalence rates were unadjusted.

Among adults aged ≥45 years, 11.2% reported SCD, 50.6% of whom reported SCD-related functional difficulties (Table 1). SCD prevalence increased with age, from 10.4% among adults aged 45–54 years to 14.3% among those aged ≥75 years and was lower among college graduates (7.0%) than among those with less than high school education (18.2%). The prevalence of SCD-related functional difficulties among college graduates (30.8%) was half that of those without a high school diploma (64.9%). Among persons living alone, 13.8% reported SCD; 55.7% of those reported SCD-related functional difficulties (Table 1).

TABLE 1. Characteristics of adults aged ≥45 years who reported subjective cognitive decline (SCD) and associated functional limitations — Behavioral Risk Factor Surveillance System, 49 states,* Puerto Rico, and the District of Columbia, 2015–2016.

Characteristic SCD
Functional limitations among those reporting SCD
No. of respondents % (95% CI)§ No. of respondents % (95% CI)§
Overall
227,393
11.2 (10.8–11.5)
23,705
50.6 (49.0–52.2)
Age group (yrs)
45–54
48,563
10.4 (9.7–11.1)
4,868
59.8 (56.4–63.2)
55–64
68,835
11.4 (10.8–12.0)
7,081
56.9 (54.3–59.6)
65–74
64,472
9.9 (9.3–10.5)
5,978
39.3 (36.4–42.3)
≥75
45,523
14.3 (13.3–15.2)
5,778
37.5 (34.1–41.0)
Sex
Men
92,639
11.4 (10.8–11.9)
10,095
47.6 (45.3–49.9)
Women
134,743
11.0 (10.6–11.5)
13,609
53.2 (51.0–55.5)
Race/Ethnicity
White
184,742
10.8 (10.5–11.2)
18,622
44.9 (43.2–46.7)
Black
16,370
13.2 (12.0–14.3)
1,991
64.4 (59.5–69.4)
American Indian/Alaska Native
3,232
19.6 (16.0–23.2)
498
73.4 (64.8–82.1)
Asian or Native Hawaiian/Other Pacific Islander
3,223
6.8 (4.3–9.3)
261
39.7 (23.9–55.5)
Other race or multiracial
4,681
15.4 (12.6–18.2)
664
55.9 (46.0–65.8)
Hispanic
11,680
11.2 (9.8–12.7)
1,267
65.8 (58.8–72.8)
Highest education level
Less than a high school diploma
17,602
18.2 (16.8–19.5)
3,110
64.9 (60.6–69.1)
High school diploma
65,474
11.6 (11.0–12.1)
7,415
53.2 (50.6–55.8)
Some college
61,574
11.5 (10.8–12.2)
6,826
49.1 (46.0–52.1)
College graduate
82,094
7.0 (6.5–7.5)
6,290
30.8 (27.7–33.8)
Veteran status
Veteran
35,738
13.6 (12.7–14.5)
4,611
42.5 (39.0–54.1)
Not a veteran
191,434
10.8 (10.4–11.1)
19,065
52.4 (50.6–54.1)
Employment status
Employed/Self-employed
91,486
6.0 (5.7–6.4)
5,209
31.1 (28.2–33.9)
Unemployed
7,184
16.9 (14.5–19.3)
1,109
60.0 (51.5–68.5)
Homemaker
12,313
8.4 (6.9–10.0)
1,057
45.7 (36.7–54.7)
Student
431
5.8 (2.9–8.6)
40
76.3 (61.0–91.5)
Retired
94,918
11.3 (10.8–11.9)
9,934
38.2 (35.7–40.7)
Unable to work
19,832
34.8 (33.1–36.5)
6,221
79.4 (77.1–81.7)
Household status
Lives alone
78,274
13.8 (13.2–14.4)
9,640
55.7 (53.3–58.0)
Does not live alone
148,038
10.4 (9.9–10.8)
13,957
48.2 (46.2–50.2)
Any chronic disease
Yes
143,954
15.2 (14.7–15.7)
19,589
53.9 (52.2–55.6)
No 83,381 5.2 (4.8–5.7) 4,103 36.1 (32.0–40.1)

Abbreviation: CI = confidence interval.

* Includes all states except Pennsylvania.

Unweighted sample of respondents. Categories might not sum to the sample total because of missing responses.

§ Weighted percentage and 95% CI.

All persons who reported a racial group were non-Hispanic. Those who reported Hispanic ethnicity might be members of any racial group.

The prevalence of SCD varied by state (Table 2). The lowest prevalence of SCD was reported in South Dakota (6.0%), and the highest was reported in Nevada (16.3%).

TABLE 2. Reported subjective cognitive decline (SCD) among adults aged ≥45 years, by state — Behavioral Risk Factor Surveillance System, 49 states,* Puerto Rico, and the District of Columbia, 2015–2016.

State No. of respondents % (95% CI)§
Overall
254,821
11.2 (10.8–11.5)
Alabama
5,811
12.9 (11.7–14.1)
Alaska
2,044
11.3 (9.3–13.4)
Arizona
6,188
13.4 (12.1–14.8)
Arkansas
4,347
16.2 (14.2–18.2)
California
2,268
11.7 (9.7–13.8)
Colorado
4,764
10.8 (9.5–12.1)
Connecticut
4,305
7.3 (6.1–8.5)
Delaware
2,914
8.8 (7.4–10.2)
District of Columbia
3,185
12.1 (9.5–14.7)
Florida
3,555
11.3 (9.9–12.7)
Georgia
3,487
14.0 (12.4–15.7)
Hawaii
5,007
8.9 (7.8–10.0)
Idaho
3,934
10.8 (9.4–12.1)
Illinois
3,773
9.6 (8.4–10.9)
Indiana
8,689
10.5 (9.6–11.4)
Iowa
4,776
9.3 (8.2–10.4)
Kansas
4,442
9.1 (8.0–10.2)
Kentucky
7,419
12.1 (10.9–13.2)
Louisiana
3,433
14.6 (12.9–16.2)
Maine
4,676
10.3 (9.0–11.5)
Maryland
5,074
10.6 (8.8–12.5)
Massachusetts
5,916
9.3 (8.1–10.4)
Michigan
2,070
12.1 (10.2–13.9)
Minnesota
11,798
8.7 (8.0–9.3)
Mississippi
4,684
12.9 (11.5–14.4)
Missouri
5,456
10.4 (9.1–11.8)
Montana
4,473
9.8 (8.6–11.1)
Nebraska
6,405
9.4 (8.3–10.5)
Nevada
2,142
16.3 (13.3–19.4)
New Hampshire
5,125
8.9 (7.8–9.9)
New Jersey
5,637
9.1 (7.9–10.4)
New Mexico
4,507
12.5 (10.9–14.0)
New York
8,353
10.3 (8.9–11.8)
North Carolina
4,296
10.7 (9.5–11.9)
North Dakota
3,675
9.9 (8.6–11.3)
Ohio
9,464
10.7 (9.6–11.8)
Oklahoma
2,626
13.6 (11.6–15.6)
Oregon
3,675
11.3 (10.0–12.6)
Rhode Island
4,835
11.5 (10.0–12.9)
South Carolina
8,683
12.1 (11.1–13.1)
South Dakota
5,407
6.0 (4.8–7.1)
Tennessee
4,538
13.6 (12.2–15.1)
Texas
5,185
13.1 (11.3–14.9)
Utah
3,428
9.6 (8.3–10.9)
Vermont
4,991
9.8 (8.6–11.0)
Virginia
6,172
8.9 (8.0–9.8)
Washington
10,356
11.1 (10.3–11.9)
West Virginia
4,231
10 (8.9–11.1)
Wisconsin
4,512
10.9 (9.4–12.3)
Wyoming
4,438
11.2 (9.7–12.7)
Puerto Rico 3,652 6.6 (5.6–7.6)

Abbreviation: CI = confidence interval.

* Includes all states except Pennsylvania.

Unweighted sample of respondents. Categories might not sum to the sample total because of missing responses.

§ Weighted percentage and 95% CI.

Nearly twice the percentage of persons reporting SCD-related functional limitations had talked to a health care professional (58.1%) compared with those without functional limitations (30.4%) (Table 3). Among persons with a functional difficulty, 81.1% reported having given up household activities or chores because of SCD, and 73.3% reported that SCD interfered with their ability to work, volunteer, or engage in social activities.

TABLE 3. Percentage of adults aged ≥45 years with subjective cognitive decline (SCD), by SCD-related functional limitation status in preceding 12 months — Behavioral Risk Factor Surveillance System, 49 states,* Puerto Rico, and the District of Columbia, 2015–2016.

Characteristic All with SCD
With SCD and functional limitations
With SCD but no functional limitations
Unweighted no. % (95% CI) Unweighted no. % (95% CI) Unweighted no. % (95% CI)
Ever discussed SCD with a health care professional
23,853
45.4 (43.8–46.9)
11,111
58.1 (55.9–60.3)
12,398
30.4 (34.6–35.6)
Gave up household activities or chores because of SCD
23,682
40.4 (38.9–42.0)
11,078
81.1 (79.0–83.1)
12,456
§
SCD interfered with ability to work, volunteer, or engage in social activities outside the home 23,675 36.5 (35.0–38.1) 11,049 73.3 (71.4–75.3) 12,456 §

Abbreviation: CI = confidence interval.

* Includes all states except Pennsylvania.

Always, usually, or sometimes.

§ By definition.

Discussion

SCD can be a symptom of early-stage dementia conditions, including Alzheimer’s (1,2). Not everyone who reports SCD will develop dementia, but some studies have shown that half of older adults with subjective memory complaints go on to develop more severe cognitive decline within 7–18 years (1,4,5). Even without progression to more severe cognitive impairment, SCD might signify a decreased ability for self-care. Inability to perform activities important to daily living such as preparing meals or managing money affect the ability to live independently and might also affect the ability to socialize or remain fully employed.

These findings are similar to those from an analysis of persons aged ≥60 years in 21 states from the 2011 BRFSS survey, which found a 12.7% prevalence of SCD (6). In that study, the highest prevalence was among Hispanics (16.9%) and the lowest was among non-Hispanic blacks (11.8%), in contrast to the current study, which found the highest prevalence among non-Hispanic American Indians and Alaska Natives (19.6%) and the lowest among non-Hispanic Asians or Native Hawaiians/Other Pacific Islanders (6.8%). The inclusion of additional states and the expansion of the age groups might have contributed to these differences.

In both 2011 (6) and 2015–2016, a higher SCD prevalence was found among adults aged ≥75 years than among those aged 45–74 years. This is similar to the prevalence of Alzheimer’s, according to 2018 data from the Alzheimer’s Association, which found an estimated 3% of persons aged 65–74 years, 17% of persons aged 75–84 years, and 32% of persons aged ≥85 years had Alzheimer’s (1,7). This analysis found a higher prevalence of SCD and related functional limitations in persons with less formal education, similar to previously reported patterns of higher dementia prevalence in persons with less formal education (8).

Younger adults might be more likely to attribute limitations in their lifestyle to SCD or might be more sensitive to its effects. Conversely, older adults might be less aware of the effects of SCD or consider it a normal part of aging. Among persons aged 45–54 years, 10.4% reported SCD, and 59.8% of those persons reported SCD-related limitations that affected work, household chores, or social activities. Although Alzheimer’s is rare in persons aged <65 years, the finding of SCD and related functional limitations among younger adults could indicate early symptoms of cognitive decline that can be a precursor to memory disorders and dementia like Alzheimer’s. These functional limitations might have important health and economic impacts. Adults aged 45–54 years are in their prime working years, when salaries peak, workers are most productive, and when workers contribute to their retirements and consume goods and services (9). An inability to work during these years might have financial implications for these adults and their families. Persons with SCD-related functional limitations might have to reduce their time working or leave the workforce entirely; in this study, nearly three fourths of those with a functional difficulty reported that SCD interfered with their ability to engage in activities outside the home, including working.

Fewer than half (45.4%) of respondents with SCD reported speaking to a health care professional about it. More than half of those with SCD-related functional limitations reported speaking to a health care professional about SCD compared with fewer than one third of persons without such limitations, suggesting that limitations in ability to perform instrumental activities of daily living might prompt discussion with a health care professional. Persons might incorrectly believe that cognitive decline is an inevitable part of aging, which could discourage them from consulting a health care professional. CDC encourages persons with confusion or memory loss to talk to a health care professional. After evaluation, even if treatment of symptoms is not an option, early assessment of cognitive issues can facilitate addressing potential safety issues, discussion of advanced care planning, including the need for caregiving, and ensuring receipt of appropriate information and referrals (10). Early assessment is important because memory issues can affect a person’s ability to manage their health; among those reporting other chronic health conditions, 15.2% also had SCD.

The findings in this report are subject to at least three limitations. First, data on SCD are self-reported. Whereas the SCD module was cognitively tested, it is not administered alongside an objective measure of cognitive performance. Therefore, the accuracy of the reports of SCD is unknown. Second, response bias might affect response to SCD questions and might underestimate SCD prevalence. Finally, BRFSS is not administered to persons with known cognitive problems who might not generate reliable data. In addition, BRFSS is only administered to noninstitutionalized adults, excluding adults living in long-term care facilities, where a proportion of residents have SCD. Therefore, these results cannot be used to estimate the prevalence of SCD across all U.S. populations.

Cognitive decline is an important public health issue affecting older adults, their families, and their caregivers, as well as the economy and health care system. As a precursor to dementia, including Alzheimer’s, SCD can impair a person’s ability to care for themselves by limiting their ability to work, particularly those adults who report SCD in their prime working years (i.e., 45–54 years). Estimating the prevalence of SCD might allow states to plan for those who might develop dementia in the future.

Summary.

What is already known about this topic?

Subjective cognitive decline (SCD) is a form of impairment in which more frequent or worsening confusion or memory loss can affect the ability to care for oneself.

What is added by this report?

Among adults aged ≥45 years, 11.2% reported SCD, including 10.4% of adults aged 45–54 years. Among all persons who reported SCD, only 45.4% had discussed it with a health care professional.

What are the implications for public health practice?

Adults with confusion or memory loss should talk to a health care professional who can assess cognitive decline and address possible treatment of symptoms, management of other co-occurring chronic health conditions, advance care planning, and caregiving needs, and who ensures that the patient receives appropriate information and referrals.

Conflict of Interest: No conflicts of interest were reported.

Footnotes

References


Articles from Morbidity and Mortality Weekly Report are provided here courtesy of Centers for Disease Control and Prevention

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