Table 2.

A Partial List of Proteins Differentially Expressed in H292 Cells Exposed to Cigarette Smoke

Protein name	Gene symbol	Fold change	Function
S100 calcium binding protein A9	S100A9	89.6	Involved in the regulation of multiple cellular processes, including cell cycle progression and differentiation
Cytochrome P450 1A1	CYP1A1	36.6	Involved in drug metabolism, synthesis of cholesterol, steroids, and other lipids
Lipocalin 2	LCN2	29.3	Plays a role in innate immunity by limiting bacterial growth as a result of sequestering iron-containing siderophores
Sterile alpha motif domain containing 9 like	SAMD9L	22.4	Acts as a tumor suppressor and plays a key role in cell proliferation and innate immune response to viral infection
Ectodysplasin-A	EDA	17.6	Acts as a homotrimer and involved in cell–cell signaling during the development of ectodermal organs