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Journal of Virology logoLink to Journal of Virology
. 2018 Jul 17;92(15):e02176-17. doi: 10.1128/JVI.02176-17

Correction for Kumar et al., “Inflammasome Adaptor Protein Apoptosis-Associated Speck-Like Protein Containing CARD (ASC) Is Critical for the Immune Response and Survival in West Nile Virus Encephalitis”

Mukesh Kumar a,b, Kelsey Roe a,b, Beverly Orillo a,b, Daniel A Muruve c, Vivek R Nerurkar a,b, Michael Gale Jr d, Saguna Verma a,b
PMCID: PMC6052302  PMID: 30018145

AUTHOR CORRECTION

Volume 87, no. 7, p. 3655–3667, 2013, https://doi.org/10.1128/JVI.02667-12. Page 3663, Fig. 7H: The Western blots depicted in panel H of the original submission have been replaced with new blots. The original panel demonstrated that there was no significant difference in IgG levels in the brains of wild-type (WT) and ASC-knockout (ASC−/−) mice following West Nile virus (WNV) infection. However, in the original figure, the blots used in the two lanes showing mock (M)-infected (uninfected control) wild-type mouse brain protein as biological replicates for the mock-infected group were accidental duplicates from the same mouse instead of from two different mice. This was a cut-and-paste error, and the blots have been replaced in the new figure panel. The data and the interpretation of the results remain the same as described in the original paper. As shown in the new figure panel, there was no significant difference between the bands of heavy and light chain IgG in control (mock) WT and ASC−/− mouse brain lysates, and the increase in IgG at day 8 (D8) after WNV infection was also comparable in WT and ASC−/− mouse brain lysates, thus supporting our overall conclusions.

Figure 7H should appear as shown below.

graphic file with name zjv0151837110007.jpg


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