Panels A and B illustrate the day-to-day profile for 20 days of baseline (i.e., on 0.3% salt diet) mean arterial blood pressure (MABP) in wildtype Dahl SS rats (WT) versus A2A knockout Dahl SS rats (A2A−/−). Panels A, B, C, and D summarize the 20-day average MABP (C), systolic blood pressure (SBP, D), diastolic blood pressure (DBP, E), and heart rate (HR, F) in female and male wildtype (+/+) versus A2A knockout (−/−) Dahl SS rats. P-values are from 2-factor analysis of variance. Values are means ± SEM.