Skip to main content
The Journal of Biological Chemistry logoLink to The Journal of Biological Chemistry
. 2018 Jul 20;293(29):11650. doi: 10.1074/jbc.W118.004643

hSos1 contains a new amino-terminal regulatory motif with specific binding affinity for its pleckstrin homology domain.

Rocío Jorge, Natasha Zarich, José Luis Oliva, Marta Azañedo, Natalia Martínez, Xavier de la Cruz, José M Rojas
PMCID: PMC6065192  PMID: 30030385

VOLUME 277 (2002) PAGES 44171–44179

This article has been withdrawn by the authors (although Rocío Jorge could not be reached and Natalia Martínez passed away). The authors have become aware of errors in the preparation of Figs. 2A, 3A, 4A, and 5A, where some lanes appear to be duplicated. The authors state that although replicated experiments performed at the time of the article as well as subsequent data published by other groups (Sondermann, H., Nagar, B., Bar-Sagi, D., and Kuriyan, J. (2005) Computational docking and solution x-ray scattering predict a membrane-interacting role for the histone domain of the Ras activator son of sevenless. Proc. Natl. Acad. Sci. U.S.A. 102, 16632–16637; Yadav, K. K., and Bar-Sagi, D. (2010) Allosteric gating of Son of sevenless activity by the histone domain. Proc. Natl. Acad. Sci. U.S.A. 107, 3436–3440; and Tartaglia, M., Pennacchio, L. A., Zhao, C., Yadav, K. K., Fodale, V., Sarkozy, A., Pandit, B., Oishi, K., Martinelli, S., Schackwitz, W., Ustaszewska, A., Martin, J., Bristow, J., Carta, C., Lepri, F., Neri, C., Vasta, I., Gibson, K., Curry, C. J., Siguero, J. P., Digilio, M. C., Zampino, G., Dallapiccola, B., Bar-Sagi, D., and Gelb, B. D. (2007) Nat. Genet. 39, 75–79) support the results and conclusions presented in this published paper, they consider that the responsible course of action is to withdraw the article in the interests of maintaining the publication standards of the journal. The authors apologize for any inconvenience they may have caused. The paper with the corrected figures can be obtained by contacting the authors.


Articles from The Journal of Biological Chemistry are provided here courtesy of American Society for Biochemistry and Molecular Biology

RESOURCES