Table 4.
Exploratory study, intravenous infection in presence and absence of trauma: systemic tissue data.
| Number (%) of mice with viable GAS in tissues |
||||||
|---|---|---|---|---|---|---|
| Blood |
Spleen |
Liver |
||||
| Time (h) from defined injury to infection | Trauma | Control | Trauma | Control | Trauma | Control |
| 0* | 4/5 (80%) |
4/4 (100%) |
4/5 (80%) |
(3/4) (75%) |
3/5 (60%) |
2/4 (50%) |
| 24 | 3/6 (50%) |
4/6 (67%) |
5/6 (83%) |
5/6 (83%) |
4/6 (67%) |
4/6 (67%) |
| 48** | 4/4 (100%) |
5/5 (100%) |
4/4 (100%) |
5/5 (100%) |
2/4 (50%) |
5/5 (100%) |
n = 6/group* 1/6 in the trauma group and 2/6 in the control (uninjured) groups reached humane end points prior to end of study.
**2/6 in the trauma group and 1/6 in the control (uninjured) group reached humane end points prior to end of study