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| |||||||
| Compound | R 1 | R 2 | Nek1 % Inh at 1 μM | Compound | R 1 | R 2 | Nek1 % Inh at 1 μM |
| UNC5078 |
|
|
91.9 | UNC5276 |
|
|
37 |
| UNC5436 |
|
|
79 | UNC5108 |
|
|
15 |
| UNC5265 |
|
|
74 | UNC5315 |
|
|
13 |
| UNC5196 |
|
|
72 | UNC5471 |
|
|
0 |
| UNC5503 |
|
|
71 | UNC5466 |
|
|
0 |
| UNC5176 |
|
|
54 | UNC5412 |
|
|
0 |
| UNC5041 |
|
|
48 | UNC5027 |
|
|
0 |
