Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
| |||
| Compound | R | clog P (log D) | Nav1.3 IC50 (nM) |
| 11 |
|
3.8 (3.3) | 17 |
| 12 |
|
3.5 (2.5) | 147 |
| 13 |
|
2.6 (1.8) | 2506 |
| 14 |
|
3.7 (ND) | 155 |
| 15 |
|
3.2 (ND) | 160 |
| 16 |
|
4.1 (ND) | 45 |
| 17 |
|
3.6 (ND) | 124 |
| 18 |
|
2.9 (ND) | 3790 |
| 19 |
|
2.6 (ND) | 4450 |
| 20 |
|
4.0 (2.6) | 197 |
| 21 |
|
4.3 (3.1) | 20 |
| 22 |
|
4.5 (3.3) | 11 |
