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. Author manuscript; available in PMC: 2018 Dec 13.
Published in final edited form as: Nature. 2018 Jun 13;558(7710):445–448. doi: 10.1038/s41586-018-0213-0

Extended Data Figure 2. Unprotected hematopoietic cells accumulate DNA-damage after UV irradiation.

Extended Data Figure 2

(a) Sorted Tg(runx:mCherry)+ cells after anti-CPD immunostain. Scale bars represent 10 μm. (b) Dot plot representation of data in Fig. 2b (quantification of immunostain intensity per cell), data are mean with s.d.; for statistics and p-values please refer to Fig. 2b. (c) Magnification of the thymus (dashed red outline) after anti-CPD immunostaining (counterstain with hemalum) after UVB irradiation at 5 dpf in pigmented and non-pigmented larvae, respectively; arrows from above indicate the melanocyte, arrows from below indicate examples of nuclei with DNA damage.