Table 7. GO annotation enriched in high-risk and low-risk groups by using GSEA.

Name	Size	ES	NES	NOM p-val	FDR q-val	FWER p-val	Rank at max	Leading edge
GO_B_CELL_RECEPTOR_SIGNALING_PATHWAY	54	0.749803	1.963207	0.003838	0.974954	0.161	6389	tags=67%, list=11%, signal=75%
GO_ADAPTIVE_IMMUNE_RESPONSE	279	0.614785	1.932954	0.007648	0.761521	0.202	7793	tags=46%, list=13%, signal=53%
GO_NEGATIVE_REGULATION_OF_INTERLEUKIN _6_PRODUCTION	33	0.711452	1.897834	0	0.660863	0.28	10264	tags=67%, list=18%, signal=81%
GO_REGULATION_OF_B_CELL_ACTIVATION	121	0.626420	1.886616	0.003883	0.617897	0.294	9579	tags=55%, list=16%, signal=65%
GO_POSITIVE_REGULATION_OF_CELL_ACTIVATION	305	0.540650	1.725436	0.031496	0.464684	0.631	11768	tags=47%, list=20%, signal=58%
GO_CELLULAR_RESPONSE_TO_ZINC_ION	16	−0.60868	−1.550511	0.056310	1	0.883	4440	tags=56%, list=8%, signal=61%
GO_RIBOSOMAL_LARGE_SUBUNIT_BIOGENESIS	48	−0.60318	−1.496404	0.109343	1	0.925	5330	tags=42%, list=9%, signal=46%
GO_POSITIVE_REGULATION_OF_PEPTIDYL_SERINE _PHOSPHORYLATION_OF_STAT_PROTEIN	21	−0.52630	−1.392874	0.115079	1	0.962	6411	tags=48%, list=11%, signal=53%
GO_RRNA_METABOLIC_PROCESS	249	−0.38387	−1.055244	0.457925	1	0.998	10606	tags=36%, list=18%, signal=44%
GO_RIBOSOME_BIOGENESIS	300	−0.38284	−1.050548	0.456692	1	0.998	11706	tags=38%, list=20%, signal=47%