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Percentage of injected dose (ID) of GDC-0449. (A) Kidney, (B) lung, (C) liver, (D) tumor, (E) heart, and (F) spleen after intravenous administration of emulsion and micellar formulations of Cy5.5-let-7b and GDC-0449 in orthotopic pancreatic tumor-bearing NSG mice. Results are represented as the mean ± S.D. (n=4).
