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. 2018 Jun 16;61(9):1966–1977. doi: 10.1007/s00125-018-4655-6

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© The Author(s) 2018

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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Fig. 2 — Time trend of age- and sex-standardised major above-the-knee amputation rate. Solid lines, people with diabetes; dashed lines, people without diabetes; circles, men and women; squares, men; triangles, women. *p < 0.05 for time trend (Poisson model)