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. Author manuscript; available in PMC: 2019 Aug 1.
Published in final edited form as: Hepatology. 2018 Jun 6;68(2):473–484. doi: 10.1002/hep.29891

Figure 5. Kinetics of HBV in serum and liver of chimeric mice after HBV inoculation.

Figure 5

Chimeric mice (5YM, n=22, #1–22) were infected with HBV and necropsied at 2 (n=3), 4 (n=4), 6 (n=4), 8 (n=4), 10 (n=2), and 13 (n=5) weeks after inoculation. Real-time qPCR was performed to measure the levels of (A) serum HBV DNA, (B) total intrahepatic HBV DNA, (C) total intrahepatic HBV RNA, and (D) intrahepatic cccDNA. Detected (*) but lower than quantification (----) and not determined (#).