Table 7.
Examples of commercially available solid dispersion products.
| Order | Products | API | Excipient | Manufacturing Method | Dosage Form | Company |
|---|---|---|---|---|---|---|
| 1 | Afeditab | Nifedipine | Poloxamer/PVP | Spray drying | Tablet | Elan |
| 2 | Afinitor | Everolimus | Hydroxypropyl methylcellulose | Spray dried | Tablet | Novartis |
| 3 | Certican | Everolimus | Hydroxypropyl methylcellulose | Spray dried | Tablet | Novartis |
| 4 | Cesamet | Nabilone | PVP | - | Tablet | Valeant |
| 5 | Crestor | Rosuvastatin | HPMC | Spray drying | Tablet | AstraZeneca |
| 6 | Florfenicol | Florfenicol | Enteric cellulose | - | Powder | Hebei Huaqiang |
| 7 | Gris-PEG | Griseofulvin | PEG-6000 | Melt-extrusion | Tablet | Pedinol |
| 8 | Incivek | Teleprevir | HPMCAS-M | Spray drying | Tablet | Vertex |
| 9 | Intelence | Etravirin | HPMC | Certican | Tablet | Tibotec |
| 10 | Isoptin | Verapamil | HPC/HPMC | Spray drying | Tablet | Abbvie |
| 11 | Kaletra | Lopinavir | PVP | Melt extrusion | Capsule | Abbvie |
| 12 | Kalydeco | Ivacaftor | HPMCAS | Spray drying | Tablet | Vertex |
| 13 | Nivadil | Nivaldipine | HPMC | Spray drying | Tablet | Fujisawa |
| 14 | Novir | Ritonavir | PVP | Melt-extrusion | Tablet | Abbott |
| 15 | Onmel | Itraconazole | HPMC | Melt-extrusion | Tablet | Sebela |
| 16 | Prograf | Tacrolimus | HPMC | Spray drying | Capsule | Fujisawa |
| 17 | Rezulin | Troglitazone | HPMC | Spray drying | Tablet | Parke Davis |
| 18 | Shuilinjia | Silibinin | Lecithin | - | Capsules | Tianjin Tasly |
| 19 | Sporanox | Itraconazole | HPMC | Spray drying on sugar beads | Capsule | Janssen |
| 20 | Stivarga | Regorafenib | Povidone K25 | - | Tablet | Bayer |
| 21 | Votubia | Everolimus | Hydroxypropyl methylcellulose | Spray dried | Tablet | Novartis |
| 22 | Zelboraf | Vemurafenib | Hypromellose acetate succinate | Precipitation | Tablet | Roche |
| 23 | Zortess | Everolimus | HPMC | Spray drying | Tablet | Novartis |