DM |
diabetes mellitus |
HFD |
high-fat diet |
CON |
control |
qRT-PCR |
quantitative real-time polymerase chain reaction |
UGT/Ugt |
UDP-glucuronosyltransferase |
STZ |
streptozotocin |
HOMA-IR |
homeostasis model assessment of insulin resistance |
i.v. |
intravenous |
p.o. |
peroral |
AUC0–t
|
area under the curve of 0 to time t |
AUC0–∞
|
area under the curve of 0 to time infinity |
MRT0–t
|
mean residence time of 0 to time t |
t1/2z
|
half time |
CLz
|
clearance |
Cmax
|
peak concentration |
Vz
|
apparent volume of distribution |
CLz/F |
clearance divided by absorption fraction |
Vz/F |
apparent volume of distribution divided by absorption fraction |