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. 2018 Jun 20;23(6):1487. doi: 10.3390/molecules23061487
DM diabetes mellitus
HFD high-fat diet
CON control
qRT-PCR quantitative real-time polymerase chain reaction
UGT/Ugt UDP-glucuronosyltransferase
STZ streptozotocin
HOMA-IR homeostasis model assessment of insulin resistance
i.v. intravenous
p.o. peroral
AUC0–t area under the curve of 0 to time t
AUC0–∞ area under the curve of 0 to time infinity
MRT0–t mean residence time of 0 to time t
t1/2z half time
CLz clearance
Cmax peak concentration
Vz apparent volume of distribution
CLz/F clearance divided by absorption fraction
Vz/F apparent volume of distribution divided by absorption fraction