Figure 7.
Docking analysis of the most active (IC50 2.5 µM) compound, 9, (A,A′) and the less active, (IC50 156.25 µM) compound 11 (B,B′) with the active site of the human 5-LOX structure PDB ID: 3V99 (target box 30). Green: hydrogen bond interactions, blue: polar interactions, yellow: pi interactions, brown: hydrophobic interactions.