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. 2018 Jul 10;23(7):1674. doi: 10.3390/molecules23071674

Figure 3.

Figure 3

Treatment of Cryptococcus neoformans infection with different doses of prosopilosidine administered for 5 days in a murine model. Graph showing live colony forming units (CFU) of C. neoformans per gram of brain tissue with percent reduction in infection by prosopilosidine treatment given at doses 0.03125, 0.06215, 0.125, 0.25, 0.5, and 1.0 mg/kg body weight as compared to the vehicle control. Amp B: Amphotericin B (1.5 mg/kg body weight). Data are shown as mean + SEM (n = 5) and was analyzed with ANOVA. ** p < 0.01, *** p < 0.001 is considered statistically significant compared to the vehicle control.