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. 2018 Jul 10;23(7):1674. doi: 10.3390/molecules23071674

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© 2018 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Cryptococcus neoformans infection in mice treated with prosopilosidine given via the oral route. Graph showing live colony forming units (CFU) of C. neoformans per gram of brain tissue and the percent reduction in infection by prosopilosidine treatment given at doses 2.5, 5.0, and 10.0 mg/kg body weight and Fluconazole (Flu) (15 mg/kg body weight) as compared to the vehicle control. Data are shown as mean ± SEM (n = 5) and was analyzed with ANOVA. *** p < 0.001 was considered significant as compared to the vehicle control.