DDR |
DNA damage response |
FDA |
Food and Drug Administration (United States) |
HAT |
Histone acetyltransferase |
HATi |
HAT inhibitors |
HDAC |
Histone de-acetyltransferase |
HDACi |
Histone de-acetyltransferase inhibitor |
HMT |
Histone methyltransferases |
KDM |
Lysine demethylases |
DSB |
Double strand break |
SSB |
Single Strand Break |
SSA |
Single Strand Annealing |
HR |
Homologous recombination |
NHEJ |
Non-Homologous End Joining |
CA |
Centrosome Amplification |
PARPi |
PARP inhibitors |
ATM |
Ataxia-telangiectasia mutated |
ATR |
Ataxia and Rad3-related |
PIKK |
Phosphatidylinositol 3-kinase-related kinase |
IR |
Ionizing radiation |
FA |
Fanconi Anemia |
MMC |
Mitomycin C |
MMEJ |
Microhomology-Mediated End Joining |
PTM |
Post translational modifications |