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. 2018 May 8;23(5):1113. doi: 10.3390/molecules23051113

Table 1.

Chemical structures and activities of steroid alkaloids used for 3D quantitative structure–activity relationships (QSAR) studies.

Compounds pIC50 (Tbr) pIC50 (L6) Compounds pIC50 (Tbr) pIC50 (L6)
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1 		6.3958 5.2928 Inline graphic
10 		5.1326 * 4.3800 *
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2 		5.3159 4.8135 Inline graphic
11 		6.7781 4.2972
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3 		7.1249 * 5.6057 * Inline graphic
12 		6.7781 * 4.5618
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4 		6.4320 4.7993 * Inline graphic
13 		6.3778 4.2130
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5 		6.1726 * 4.7707 Inline graphic
14 		6.9245 4.8444
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6 		5.9190 4.7603 Inline graphic
15 		5.7807 4.0103 *
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7 		4.8282 * n.t Inline graphic
16 		5.0856 3.7426
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8 		5.0624 4.1816 Inline graphic
17 		4.6798 3.9045
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9 		4.7568 3.8897

* Test set compounds; pIC50 = −log(IC50) as used in the comparative molecular field analysis (CoMFA) analysis; n.t = not tested.