Figure 1. mRNA m6A levels are decreased in immortalized and transformed HMECs but increased by hypoxia.

LC-MS/MS of mRNA nucleosides isolated from primary, immortalized, and transformed HMECs grown in normoxia or hypoxia (1% O₂) for 24 hours. Values represent the amount of m6A relative to total Adenosine content. ^*P ≤ 0.05, ^@P ≤ 0.1 by paired Student's t-test. Error bars represent standard error of the mean (SEM) of 3 experiments.