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Elevated intracellular c-di-GMP levels alleviate the need for a functional cysD for calcium-induced PbrpA expression. PbrpA lacZ expression in the wild type and cysD mutant under unaltered (v [empty vector]) or elevated (DcpA) intracellular c-di-GMP levels. Statistically significant differences among the samples (P < 0.001 as determined by one-way ANOVA followed by pairwise comparisons with a Bonferroni adjustment) are indicated by different symbols above each bar.
