Key resources table.
| Reagent type (species) or resource |
Designation | Source or reference | Identifiers | Additional information |
|---|---|---|---|---|
| Gene (Mus musculus) |
Tor1a | NA | NCBI Gene: 30931; MGI:1353568 |
Encodes TorsinA |
| Strain, strain background(M. musculus) |
ChAT-Cre | Jackson Laboratories | Stock ID 006410 | Chattm2(cre)Lowl; (Chat-IRES-Cre) |
| Strain, strain background(M. musculus) |
Tor1aFlx/Flx | Jackson Laboratories | Stock ID 025832 | Tor1atm3.1Wtd |
| Strain, strain background(M. musculus) |
Tor1a-/- | Jackson Laboratories | Stock ID 006251 | Tor1atm1Wtd |
| Antibody | Choline Acetyltransferase |
Millipore AB144P | RRID: AB_2079751 | 1:100 |
| Antibody | P75 Neurotrophin Receptor |
Santa Cruz sc6188 | RRID: AB_2267254 | 1:100 |
| Antibody | NeuN | Cell Signaling #12943 | RRID: AB_2630395 | 1:500 |
| Antibody | GFAP | Cell Signaling #3670P | RRID: AB_561049 | 1:1000 |
| Antibody | Iba-1 | Wako 019–19741 | RRID: AB_839504 | 1:500 |
| Antibody | TorsinA | Abcam ab34540 | RRID: AB_2240792 | 1:100 |
| Antibody | anti-mouse | ThermoFisher A-31571 |
RRID: AB_162542 | 1:800 |
| Antibody | anti-rabbit | ThermoFisher A-21206 |
RRID: AB_2535792 | 1:800 |
| Antibody | anti-rabbit | ThermoFisher A-31572 |
RRID: AB_162543 | 1:800 |
| Antibody | anti-goat | ThermoFisher A-21432 |
RRID: AB_2535853 | 1:800 |
| Antibody | anti-goat | Jackson Immunoresearch 705-065-003 |
RRID: AB_2340396 | 1:800 |
| Commercial assay or kit |
ABC HRP Kit (Standard) |
Vector Laboratories | Pk-6100 | Vectastain elite ABC kit |