Fig. 2.

Glucose reabsorption by the proximal tubule. (a) Schematic representation of a single nephron, the functional unit of the kidney. (b) Glucose concentration (mmol/l) measured in micropuncture studies as fluid flows from the glomerulus along the tubule [51]. SGLT2 and GLUT2 are responsible for glucose reabsorption in the S1 and S2 segments, and SGLT1 and GLUT2 are responsible for glucose reabsorption in the S3 segment . Adapted from [6], distributed under the terms of the CC BY 4.0 Attribution License (http://creativecommons.org/licenses/by/4.0/). This figure is available as part of a downloadable slideset