Table 2. Primary and Secondary Outcomes by Type of Intervention.
| Type of Intervention | Date of Operation |
Patient No. |
Hospital Length of Stay, d |
Primary Oucome: 90-d Mortality |
Secondary Outcome: 90-d Morbidity |
Cancer Pathology | Type of Postoperative Cancer Treatment |
|---|---|---|---|---|---|---|---|
| Tracheal transplantation | Oct 2010 | 2 | 14 | No | No | NA | NA |
| Tracheal transplantation | Jan 2011 | 3 | 11 | No | No | NA | NA |
| Tracheal transplantation | Oct 2011 | 4 | 10 | No | No | NA | NA |
| Tracheal transplantation | Jun 2016 | 17 | 6 | No | Subcutaneous emphysema | R0 resectiona | None |
| Tracheal transplantation | Feb 2017 | 20 | 10 | No | Tracheal granuloma, laryngeal edema at months 2 and 3, bronchoscopy, and tracheostomy | R0 resectiona | None |
| Venovenous ECMO, right pneumonectomy extended to trachea, and carinal transplantation | May 2012 | 6 | NA | Yes on day 1 | Cerebrovascular accident and intracranial carotid artery occlusion | Pathological T4N2M0 | NA |
| Intrapericardial upper bilobectomy and bronchial transplantation | Oct 2009 | 1 | 16 | No | Atrial fibrillation, acute lung edema, atelectasis, and urinary retention | Pathological T4N0M0 | None |
| Left upper lobectomy and bronchial transplantation | Oct 2012 | 7 | 12 | No | Atelectasis | Clinical T2N2M0 and pathological T3N0M0 | Radiotherapy |
| Left lower lobectomy and bronchial and pulmonary artery transplantation | Jan 2013 | 8 | 8 | No | No | Clinical T2N2M0 and pathological T2N1M0 | Radiotherapy |
| Intrapericardial upper bilobectomy and bronchial transplantation | Mar 2013 | 9 | 9 | No | No | Clinical T3N1M0 and pathological T3N1M0 | None |
| Right lower lobectomy and bronchial and pulmonary artery transplantation | Dec 2013 | 10 | 22 | No | Atrial fibrillation and acute respiratory distress syndrome | 2 Atypical carcinoid tumors: pathological T3N0M0 | None |
| Lower bilobectomy and bronchial transplantation | Nov 2014 | 13 | 12 | No | Atelectasis | Clinical T3N0M0 and pathological T3N1M0 | Radiotherapy |
| Lower bilobectomy and bronchial transplantation | Jan 2015 | 14 | 9 | No | Anemia necessitating blood transfusion | Clinical T3N0M0 and pathological T0N0M0 | Radiotherapy |
| Standard lobectomy but transplantation not performed | Apr 2014 | 12 | 10 | No | No | Pathological T2N0M0 | None |
| Standard lobectomy but transplantation not performed | Mar 2016 | 15 | 6 | No | No | Pathological T2N2M0 | Radiochemotherapy |
| Standard lobectomy extended to thoracic wall but transplantation not performed | Jul 2016 | 19 | 9 | No | No | Clinical T3N0M0 and pathological T3N0M0 | Radiotherapy |
| Pneumonectomy but transplantation not performed | Apr 2016 | 16 | 11 | No | Atrial fibrillation | Pathological T2N1M0 | None |
| Exploratory thoracotomy but transplantation not performed | Jun 2014 | 11 | 8 | No | No | Clinical T4N2M0 | Radiochemotherapy |
| Exploratory thoracotomy but transplantation not performed | Jun 2016 | 18 | 6 | No | No | Clinical T4N2M0 | Radiochemotherapy |
| Myocardial ischemia but operation not performed | Jul 2011 | 5 | NA | No | No | Clinical T3N2M0 | NA |
Abbreviations: ECMO, extracorporeal membrane oxygenation; NA, not applicable.
a
Indicates no residual tumor was found during pathological examination of the resected specimens.