Table 2.
A) MV with high expression of ectoenzymes in MM patients and controls (% of MV with high expression; mean ± SD) |
MM patients |
MGUS/SMM patients |
Statistics |
CD38 | 33.3 ± 4.1 | 17.9 ± 3.4 | p = 0.006 |
CD39 | 22.9 ± 3.9 | 13.2 ± 2.5 | p = 0.05 |
CD157 | 24.7 ± 3.8 | 13 ± 2.3 | p = 0.04 |
CD203a/PC-1 | 21.3 ± 3.7 | 12.2 ± 3.1 | p = 0.04 |
CD73 | 25.3 ± 3.5 | 14.5 ± 3.2 | p = 0.01 |
B) MV with high expression of ectoenzymes in BM cells from MM patients (% of MV with high expression; mean ± SD) |
CD138+ cells |
CD138- cells |
Statistics |
CD38 | 28 ± 1.1 | 4.6 ± 0.32 | p = 0.05 |
CD39 | 16.3 ± 0.3 | 10.5 ± 0.3 | p = 0.05 |
CD73 | 4.4 ± 0.3 | 6.6 ± 0.3 | p = 0.05 |
CD203a/PC-1 | 16.9 ± 0.5 | 16.4 ± 0.3 | ns |
C) MV with high expression of ectoenzymes in fresh BM samples from MM patients and controls (% of MV with high expression; mean ± SD) |
MM patients |
MGUS/SMM patients |
Statistics |
CD38 | 37 ± 16.9 | 7.3 ± 0.69 | p = 0.05 |
CD39 | 31.4 ± 12.1 | 2.4 ± 0.17 | p = 0.05 |
CD203a/PC-1 | 43.1 ± 16.2 | 2.5 ± 0.2 | p = 0.05 |
CD73 | 48.7 ± 11.3 | 4.5 ± 1.3 | p = 0.05 |