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. 2018 Oct;24(10):1277–1284. doi: 10.1261/rna.067736.118

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© 2018 Han and Phizicky; Published by Cold Spring Harbor Laboratory Press for the RNA Society

This article is distributed exclusively by the RNA Society for the first 12 months after the full-issue publication date (see http://rnajournal.cshlp.org/site/misc/terms.xhtml). After 12 months, it is available under a Creative Commons License (Attribution-NonCommercial 4.0 International), as described at http://creativecommons.org/licenses/by-nc/4.0/.

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FIGURE 2. — Schematic of the five anticodon loop circuits discussed in this review. (A) Cm₃₂ and Gm₃₄ drive yW₃₇ formation in tRNA^Phe of S. pombe, S. cerevisiae, and humans. (B) i⁶A₃₇ drives m³C₃₂ formation in tRNA^Ser of S. pombe and S. cerevisiae, and t⁶A₃₇ drives m³C₃₂ formation in tRNA^Thr of S. cerevisiae. (C) i⁶A₃₇ drives Cm₃₄ and Um₃₄ formation in tRNA^Leu(CAA) and tRNA^Leu(UAA) of E. coli. (D) Q₃₄ drives m⁵C₃₈ formation in tRNA^Asp of S. pombe and D. discoideum. (E) C₃₂ to m³C₃₂ to m³U₃₂ drives I₃₄ formation in tRNA^Thr(AGU) of T. brucei.