Table 3. Muscle apparent rate constants derived from sinusoidal analysis (Kawai and Brandt, 1980).

Means ± S.E.M are reported. Student’s t-test with p<0.05 significantly different from control (*p<0.05, **p<0.01, ***p<0.001). N = 12 for control and mutant heterozygotes; N = 16 for mutant homozygotes (see Figure 5—figure supplement 1 for an explanation of how the apparent rate constants relate to the cross-bridge cycle). Full genotypes given in legend to Table 1.

Line	A	B	2πb (s -1)	C	2πc (s -1)
PwMhc2 control	339 ± 23	741 ± 73	1036 ± 35	923 ± 76	5376 ± 169
R146N-15/+ heterozygote	305 ± 33	832 ± 75	1343 ± 52***	1009 ± 85	4928 ± 262
R146N-15 homozygote	304 ± 33	751 ± 87	1224 ± 80	934 ± 93	4671 ± 232*