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. 2018 Sep;276:74–82. doi: 10.1016/j.atherosclerosis.2018.07.019

Fig. 2.

Fig. 2

BMT reduces Ang II-mediated accelerated atherosclerosis and macrophage content in 0.8 mg/kg/day Ang II-treated ApoE−/− mice.

(A) Atherosclerotic plaque in the aortic roots of 18-week old BMT and non-BMT mice following Ang II (0.8 mg/kg/day) infusion for 14 days. Mice were kept on a chow diet. Microscopy of Massons trichrome stained aortic root lesions. (B) Galectin-3 positive macrophage content in the aortic roots of 18-week old BMT and non-BMT mice following Ang II (0.8 mg kg−1 per day) infusion for 14 days. Microscopy of Galectin3 (Gal-3) stained aortic root lesions. (n = 4–6 per group) *p < 0.05. (C) Atherosclerotic plaque in the aortic roots of 18-week old BMT mice following Ang II infusion II (0.8, 1.5, or 3 mg/kg/day) for 14. days. (D) Galectin-3 positive macrophage content in the aortic roots of 18-week old BMT mice following Ang II infusion (0.8, 1.5, or 3 mg/kg/day) for 14 days.