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. 2018 Sep 4;9(69):33064–33076. doi: 10.18632/oncotarget.25869

Figure 4. Top scoring molecular pathways for transcription, translation and translation efficiency by Ingenuity Pathway Analysis for carboplatin + INK128 treated OVCAR-3 cells.

Figure 4

Results represent the number of mRNAs scoring in each of the top ranked pathways and the range of P-values. A. Transcription analysis: mRNAs altered in abundance alone. B. Translation analysis: mRNAs altered in heavy polysome association (≥4 ribosome heavy polysome/total mRNA) regardless of total mRNA abundance. C. Translation efficiency analysis: ratio of heavy polysome/total mRNA.