Table 6.
Antimicrobial activity of the Schiff base ligand and its metal complexes.
| Compound | Micro-organism | ||
|---|---|---|---|
|
Staphylococcus aureus ATCC* 6538 |
Escherichia. coli ATCC* 8739 |
Candida albicans ATCC* 10231 |
|
| C16H12N3Cl (HL) | ++ | + | ++ |
| [Cu((L)2]·EtOH (1) C34H28N6OCl2Cu |
+++ | +++ | ++ |
| [Ni(L)2(OH2)2]·2EtOH (2) C36H38N6O4Cl2Ni |
++++ | +++ | ++ |
| [Co(L)2(OH2)2] (3) C32H26N6O2Cl2Co |
+++ | ++ | +++ |
| [Mn(L)2(OH2)2] (4) C32H26N6O2Cl2Mn |
++++ | +++ | +++ |
| [Fe(L)2(Cl)(OH2)2]·3EtOH (5) C38H44N6O5Cl3Fe |
+++ | +++ | ++++ |
| [UO2(L)2(OEt)]·EtOH (6) C36H33N6O4Cl2U |
+++ | +++ | ++ |
| Streptomycin | ++++ | +++ | +++ |
* number of strain in the ATCC collection
(a) S. aureus, (b) E. coli, (c) = C. Albicans. Inhibition zone diameter in nm (% inhabitation): +, 8-10 (36-45%); ++, 10-16 (45-73%); +++, 16-19 (73-86); ++++, 19-22 (86-100%). Percent inhibition values are relative to the zone (22 mm) with 100% inhabition.