Table 1.
Comp. | MAO A Inhibition % | MAO B Inhibition % | ||
---|---|---|---|---|
10−3 M | 10−4 M | 10−3 M | 10−4 M | |
3a | 25.00 | 19.02 | 60.37 | 52.15 |
3b | 30.08 | 20.45 | 30.46 | 26.88 |
3c | 14.10 | 10.75 | 25.75 | 18.20 |
3d | 18.88 | 12.71 | 23.97 | 17.75 |
3e | 22.12 | 18.55 | 87.28 | 83.50 |
3f | 30.77 | 18.30 | 75.66 | 68.30 |
3g | 16.69 | 11.07 | 18.20 | 11.23 |
3h | 25.89 | 21.30 | 82.58 | 79.10 |
3i | 19.88 | 10.55 | 32.02 | 28.75 |
3j | 22.15 | 17.28 | 34.60 | 30.50 |
Moclobemide | 91.42 ± 4.60 | 77.86 ± 3.71 | - | - |
Selegiline | - | - | 97.69 ± 4.16 | 94.42 ± 3.89 |