Table 1.
1H-NMR (600 MHz) spectroscopic data for compounds 1–5 in CD3OD (δH, J in Hz).
| Position | 1 | 2 | 3 | 4 | 5 |
|---|---|---|---|---|---|
| 1a | 1.62, m | 1.60, m | 1.55, m | 1.55, m | 1.58, m |
| 1b | 1.00, m | 0.98, m | 0.95, m | 0.93, m | 0.95, m |
| 2a | 1.98, m | 1.96, m | 1.78, m | 1.80, m | 1.78, m |
| 2b | 1.72, m | 1.70, m | 1.70, m | 1.76, m | 1.68, m |
| 3 | 3.19, dd (11.7, 4.3) | 3.13, dd (11.8, 4.4) | 3.07, dd (9.9, 5.7) | 3.07, dd (9.9, 5.7) | 3.14, dd (11.2, 4.6) |
| 5 | 0.81, m | 0.77, m | 0.75, m | 0.75, m | 0.76, m |
| 6a | 1.59, m | 1.57, m | 4.51, br s | 4.51, br s | 1.57, m |
| 6b | 1.45, m | 1.43, m | 1.43, m | ||
| 7a | 1.43, m | 1.41, m | 1.72, m | 1.73, m | 1.55, m |
| 7b | 1.27, m | 1.25, m | 1.55, m | 1.58, m | 1.36, m |
| 9 | 1.58, m | 1.56, m | 1.58, m | 1.58, m | 1.54, m |
| 11a | 1.93, m | 1.92, m | 2.03, m | 2.02, m | 1.92, m |
| 11b | 1.92, m | 1.91, m | 1.91, m | 1.90, m | 1.85, m |
| 12 | 5.34, t-like (1.5) | 5.31, t-like (1.5) | 5.27, br s | 5.27, br s | 5.34, br s |
| 15a | 1.82, m | 1.79, m | 1.80, m | 1.40, m | 1.40, m |
| 15b | 1.53, m | 1.51, m | 1.25, m | 1.20, m | 1.21, m |
| 16 | 4.32, dd (11.9, 4.5) | 4.29, dd (12.0, 4.6) | 4.13, dd (11.4, 4.5) | 4.24, dd (11.7, 4.8) | 4.24, dd (12.0, 4.8) |
| 18 | 2.78, dd (14.0, 4.2) | 2.76, dd (14.0, 4.5) | 2.18, m | 2.21, m | 2.18, m |
| 19a | 1.70, m | 1.67, m | 1.73, m | 1.72, m | 1.71, m |
| 19b | 1.19, m | 1.16, m | 1.03, m | 1.06, m | 1.02, m |
| 21a | 1.58, m | 1.56, m | 1.90, m | 1.41, m | 1.41, m |
| 21b | 1.37, m | 1.34, m | 1.15, m | 1.21, m | 1.21, m |
| 22a | 2.09, m | 2.06, m | 1.39, m | 2.21, m | 2.10, m |
| 22b | 1.26, m | 1.23, m | 1.11, m | 1.41, m | 1.40, m |
| 23 | 1.08, s | 1.05, s | 1.13, s | 1.13, s | 1.06, s |
| 24 | 0.88, s | 0.85, s | 1.23, s | 1.23, s | 0.86, s |
| 25 | 0.98, s | 0.95, s | 1.33, s | 1.33, s | 0.97, s |
| 26 | 0.83, s | 0.81, s | 1.28, s | 1.30, s | 1.03, s |
| 27 | 1.25, s | 1.23, s | 1.19, s | 1.20, s | 1.24, s |
| 28a | 9.76, s | 9.73, s | 0.79, s | 3.80, d (9.7) | 3.81, d (9.7) |
| 28b | 3.26, m | 3.27, m | |||
| 29 | 0.96, s | 0.93, s | 0.89, s | 0.90, s | 0.90, s |
| 30 | 0.96, s | 0.94, s | 0.92, s | 0.93, s | 0.92, s |
| GluA-1′ | 4.38, d (8.2) | 4.37, d (7.8) | 4.37, d (7.7) | 4.37, d (7.8) | 4.40, d (7.5) |
| 2′ | 3.24, t (8.3) | 3.22, t (8.5) | 3.24, t (8.4) | 3.24, t (8.4) | 3.26, t (8.4) |
| 3′ | 3.39, t (9.2) | 3.34, t (9.1) | 3.35, t (9.1) | 3.35, t (9.1) | 3.37, t (9.0) |
| 4′ | 3.47, t (8.8) | 3.49, t (9.4) | 3.50, t (9.4) | 3.49, t (9.4) | 3.53, t (9.2) |
| 5′ | 3.62, d (10.0) | 3.81, d (9.8) | 3.80, d (9.8) | 3.80, d (9.7) | 3.83, br d (10.0) |
| 6′-OCH3 | 3.77, s | 3.76, s | 3.76, s | 3.79, s |