Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Non-compartmental pharmacokinetic parameters of berberine following oral administration in Balb/c mice.
| Suspension | A | B | C | |
|---|---|---|---|---|
| tmax (min) | 180 | 30 | 30 | 30 |
| Cmax (ng/mL) | 8.5 | 20.8 | 46.9 | 51.2 |
| t1/2 λz (min) | 208 | 268 | 248 | 265 |
| AUClast (ng min/mL) | 2226 | 1170 | 3499 | 8640 |
| AUC (ng min/mL) | 3630 | 1904 | 5112 | 14,219 |
| AUC (%Extrapolated) | 39 | 39 | 31 | 39 |
| MRT (min) | 371 | 354 | 315 | 384 |
| Fr (%) | 100 | 52 | 141 | 392 |
