Figure 2.

Effect of leaf crude extract, hexane fraction, chloroform fraction, ethyl acetate fraction, and residual fraction of S. cordifolia on PGE₂, PGD₂, TXB₂, and PGF_2α production in LPS-stimulated RAW 264.7 cells. Cells were treated with LPS in the absence or presence of the fractions at two concentrations (10 and 50 µg/mL). DEX was used as positive control. After incubation, cell culture supernatants were harvested, and PGE₂, PGD₂, TXB₂, and PGF_2α production was determined. Values are expressed as mean ± SD. * p < 0.001 vs. control (LPS alone).