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. 2018 Sep 20;6:e5632. doi: 10.7717/peerj.5632

Figure 2. Nociceptor-specific overexpression of Gαq causes hypersensitivity to noxious thermal and mechanical stimuli.

Figure 2

(A) Larvae with nociceptor-specific overexpression of Gαq showed a significantly shorter latency to respond to a noxious thermal stimulus (46 °C) than did GAL4-only or UAS-only control larvae. Response latencies of individual animals are plotted as points on the graph, while the mean for each genotype is indicated as a horizontal bar (n ≥ 50 for all groups; *p ≤ 0.05 by Wilcoxon Rank-Sum Test compared to both control genotypes). (B) A greater proportion of larvae with nociceptor-specific overexpression of Gαq responded to a noxious mechanical stimulus than did UAS-only controls (n ≥ 65 for all groups; #p ≤ 0.05 by Chi-Square Test compared to UAS-only control). Bars indicate the proportion of animals from each genotype that responded to the first application of the mechanical stimulus. Error bars indicate the standard error of the proportion.